Mechanisms of Aging and Demetina Training Program

描述(由申请人提供)：本申请是西北大学神经科学研究所(NUIN)继续资助基础广泛的博士后和博士后衰老和痴呆症机制培训计划的申请。在四名高级博士后候选人开始全日制论文研究后，以及四名博士后实习生在培训的早期或后期阶段，要求提供资金以支持他们。该培训计划由一个多学科的研究小组发展而来，他们的工作重点是衰老和痴呆症的机制，包括阿尔茨海默氏症、帕金森氏病和肌萎缩侧索硬化症，方法跨越分子、细胞、系统、行为、神经心理和临床神经科学，包括四名目前获得NIH优异奖的研究人员和一名霍华德·休斯研究员。24名教务长中有7名是女性，包括副主任。这些教员隶属于NUIN，即认知神经学和阿尔茨海默氏症中心，该中心有NIA支持的阿尔茨海默氏症中心赠款，Buehler老龄化中心和Udall Parkinson‘s疾病中心。该计划将由John Disterhoft博士指导，桑德拉·温特劳布博士(副主任)、一个内部指导委员会和一个外部咨询委员会协助。四名博士后和四名博士后实习生将在来自西北大学芝加哥和埃文斯顿校区两所学校10个系的24名教授的指导下进行研究。博士后实习生将根据之前的培训和研究计划进行挑选。博士前实习生将根据课程表现、轮换和建议的论文研究的相关性，从NUIN和医学科学家博士培训计划中挑选出来。将特别考虑那些研究计划是跨学科的，并在一个以上的教师实验室进行的受训者。将作出协调努力，招募妇女和少数族裔。该计划将在衰老和痴呆症研究的基础和临床方法方面提供广泛的跨学科研究和培训机会。导师教员将通过正式咨询和评估、通过课堂和非正式讨论来协助和监测受训人员的进展。除了提供研究培训外，该计划还将帮助学员发展书面和口头沟通、补助金撰写、网络和职业发展方面的技能。另一个培训目标将是灌输神经科学家面临的道德问题和科学中负责任的行为的清晰意识。

DESCRIPTION (provided by applicant): This application is a request for continued funding of a broadly based postdoctoral and predoctoral Mechanisms of Aging and Dementia Training Program from the Northwestern University Institute for Neuroscience (NUIN). Funding to support four advanced predoctoral candidates, after they have begun full time thesis research, and four postdoctoral trainees, in early or later stages of training, is requested. This training program has developed from a multidisciplinary group of investigators whose work focuses on the mechanisms of aging and dementia, including Alzheimer's Disease, Parkinson's Disease and Amyotrophic Lateral Sclerosis, with approaches spanning molecular, cellular, systems, behavioral, neuropsychological and clinical neuroscience, including four with current NIH MERIT awards, and one Howard Hughes Investigator. Seven of 24 faculty preceptors are women, including the Associate Director. These faculty are affiliated with NUIN, the Cognitive Neurology and Alzheimer's Disease Center, that has an NIA supported Alzheimer's Disease Center grant, the Buehler Center on Aging and the Udall Parkinson's Disease Center. The program will be directed by John Disterhoft, PhD with the assistance of Sandra Weintraub, PhD (Associate Director), an internal Steering Committee and an External Advisory Committee. The four postdoctoral and four predoctoral trainees will conduct their research under the guidance of 24 preceptors from 10 departments of 2 schools on the Chicago and Evanston campuses of Northwestern University. Postdoctoral trainees will be selected on the basis of previous training and a research plan. Predoctoral trainees will be selected from NUIN and the Medical Scientist PhD Training Program on the basis of course performance, rotation and the relevance of proposed dissertation research. Special consideration will be given to trainees whose research plans are interdisciplinary and carried out in more than one preceptor laboratory. A concerted effort will be made to recruit women and minorities. The program will offer a board range of interdisciplinary research and training opportunities in both the fundamental and clinical approaches to aging and dementia research. The preceptor faculty will assist and monitor trainee progress through formal advising and evaluations, through the classroom and through informal discussions. In addition to providing research training, the program will help trainees develop skills in written and oral communication, grant writing, networking, and career development. Instilling a clear awareness of ethical issues facing neuroscientists and responsible conduct in science will be another training goal.