Immunology and Immunooncology Training Program

描述(由申请人提供)：这是一项存在了30多年的免疫肿瘤学培训补助金的竞争性更新。通过这一工具，我们为希望成为免疫肿瘤学和免疫学独立研究人员的高级博士后和博士后学生提供高质量的培训。提供广泛的现代生物学培训，特别强调遗传、分子、细胞生物学和结构方法，以解决免疫肿瘤学和免疫学中的问题。这笔培训补助金是微生物学和免疫学、生物化学、细胞生物学、发育和分子生物学、妇科肿瘤学、核医学、妇产科/妇科、病理学和儿科系22名教职员工的培训和研究重点。我们研究和培训环境的一个重要组成部分是我们久负盛名的AECOM癌症中心，该中心由I.David Goldman博士领导。我们所有的训练师都是会员。我们的博士前项目在苏·戈尔丁研究生院的指导下进行。该计划包含仔细招生过程的基本要素，包括基础课程的核心，然后是免疫学专业课程，并辅之以研讨会、期刊俱乐部、进展中的会议、外部演讲，以及对每个博士后和博士后水平的研究项目的密切监督。贝尔福高级生物医学研究所的建立确保了博士后同事对他们的研究经验和职业机会的特别关注得到解决。我们培训计划最重要的特点是博士后和博士后学员在实验室的密集工作，从到达开始，一直在密切的监督下进行。我们的计划还包括在共享设施中包含的相关仪器的培训，包括杂交瘤设备、FACS设备、转基因小鼠和干细胞设备、X射线结晶学和分子建模、肽合成和蛋白质测序、寡核苷酸合成和DNA测序以及微阵列设备。在接下来的5年里，我们强调继续重视与癌症相关的研究，并将新的重点放在翻译和临床研究上。

DESCRIPTION (provided by applicant): This is a competitive renewal of a training grant in immuno-oncology that has been in existence for over 30 years. With this vehicle we provide high quality training for advanced predoctoral and postdoctoral students who desire careers as independent investigators in immuno-oncology and immunology. Broad training in modern biology is offered with special emphasis on genetic, molecular, cell biological and structural approaches to the solution of problems in immuno-oncology and immunology. This training grant is a focus for training and research by 22 faculty members in the Departments of Microbiology & Immunology, Biochemistry, Cell Biology, Developmental and Molecular Biology, Gynecologic Oncology, Nuclear Medicine, OB/GYN, Pathology and Pediatrics. A vital component of our research and training environment is our well-established AECOM Cancer Center headed by Dr. I. David Goldman. All our trainers are members. Our predoctoral program operates within the guidelines of the Sue Golding Graduate School. The program contains the essential elements of a careful admissions process, a core of basic courses followed by specialized courses in immunology and supplemented with seminars, journal clubs, work-in-progress sessions, outside speakers, as well as close supervision of the research program for each student at both predoctoral and postdoctoral level. Establishment of the Belfer Institute for Advanced Biomedical Studies assures that the special concerns of postdoctoral associates are addressed concerning their research experience and career opportunities. The most important feature of our training program is the intensive work in the laboratory by predoctoral and postdoctoral trainees that starts with arrival and continues under close supervision throughout. Our program also features training in relevant instrumentation contained in shared facilities including a Hybridoma facility, FACS facility, transgenic mouse and stem cell facility, X-ray crystallography and molecular modeling, peptide synthesis and protein sequencing, oligonucleotide synthesis and DNA sequencing and microarrray facilities. For the next 5 years, we stress continued emphasis on cancer relevant research and a new focus on translational and clinical research.