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中文摘要
翻译
爱因斯坦手蛋白质组研究中心的使命是评估 药物成瘾与治疗在HIV相关疾病发展中的相互作用 神经认知障碍(手)。爱因斯坦手部蛋白质组学试点的中心研究主题 研究中心(EHPRC)将重点研究艾滋病毒感染引起的机制 手的发病和进程的生物标记物,以及潜在的相加影响 丁丙诺啡利用蛋白质组学治疗手部发育进展 在人类、动物模型和细胞培养中的方法。EHPRC将提供蛋白质组学, 为三个协同项目提供生物信息学、数据整合和统计支持。科学 实验室信息管理系统将促进互动和项目整合 (LIMS),EHPRC网站,EHPRC成员每周实验室会议,以及在 与内部和外部咨询委员会举行会议。
英文摘要
The mission of the Einstein HAND Proteomics Research Center is to evaluate the interactions of drug addiction and its treatment on the development and progression of HIV associated neurocognitive disorders (HAND). The central research themes of the pilot Einstein HAND Proteomics Research Center (EHPRC) will focus on investigating the mechanism by which HIV infection causes HAND, identifying biomarkers for the onset and course of HAND and the potential additive impact of buprenorphine treatment on the development and progression of HAND by utilizing proteomic approaches in humans, animal models and cell culture. The EHPRC will provide the proteomics, bioinformatics, data integration, and statistical support for three synergistic projects. Scientific interactions and project integration will be fostered by a laboratory information management system (LIMS), an EHPRC web site, weekly lab meetings of EHPRC members, and annual presentations at meetings with internal and external advisory committees.
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Imaging Mass Spectrometry System
LTQ Orbitrap Velos Mass Spectrometer System
QTRAP 5500 Triple Quadrupole Mass Spectrometer System
Pilot Proteomics Center on Drug Abuse HIV/AIDS