Vermont Center on Behavior and Health

这是生物医学研究卓越中心(COBRE)第二阶段的应用程序，以进一步开发 佛蒙特州大学行为与健康研究中心(VCBH)。这是一个多学科的 研究中心专注于调查不健康行为模式(如物质)之间的关系 虐待、缺乏体育活动、不健康的食物选择、不遵守推荐的医疗方案)以及 有患慢性病和过早死亡的风险。最重要的科学优先事项正在：(A)增加 了解易受不健康行为模式影响的机制和(B)发展 更有效的行为改变干预措施。在这些领域中的每一个方面的进步都是改善 美国人口健康，缩小健康差距，并削减螺旋式上升的医疗保健成本。VCBH已经做出了 在第一阶段取得了相当大的进展，以期在这方面建立一个卓有成效的研究中心 生物医学研究的重要领域。VCBH目前由20名UVM教职员工组成， 优秀的外部、内部和社区顾问，以及来自其他想法国家和地区的协作者 更远一点。目前的教员是多学科的，在学术级别上均匀分布，并且高度 富有成效，在同行评议期刊上发表了118篇文章，并获得了59,135,320美元的额外收入 在第一阶段筹资的最初四年期间提供外部赠款支持。我们建议继续优先处理 在第二阶段对有前途的早期教师进行指导。我们为9名早期教师提供了 在第一阶段，使用多元指导，资助研究项目和职业发展支持 计划，我们将在拟议的资助期内继续评估和完善。我们建议继续 促进有效沟通、财政规划和监督的行政核心，支持 充满活力的知识基础设施，并指导和支持获得外部赠款支持的努力。我们有 建立了另外两个VCBH核心，我们建议继续下去，即行为经济学和干预 科学(BEIS)核心和协作、传播和教育(CDE)核心。BEIS助攻 调查人员具有决策和神经成像组件，以检查支撑过程 对不健康行为模式的脆弱性，行为改变干预措施的发展，以及经济 干预成本-效果模型。CDE支持地方、国家和国际研究 合作，通过每月系列讲座传播新知识，年度全国会议， 同行评议期刊《预防医学》年度特刊、其他出版物和教育性期刊 努力，包括在密歇根州立大学校园内提供的行为和健康方面的研讨会和研讨会 现场直播给合作者和感兴趣的其他人。我们有信心继续发展壮大 遵循这一总体管理计划，VCBH将成功地建立一个多学科中心 在行为和健康方面的卓越研究，具有可持续的地方、国家和国际影响。

This is a Phase 2 Center of Biomedical Research Excellence (COBRE) application to further develop the Vermont Center on Behavior and Health (VCBH) at the University of Vermont (UVM). This multidisciplinary research center focuses on investigating relationships between unhealthy behavior patterns (e.g., substance abuse, physical inactivity, unhealthy food choices, non-adherence with recommended medical regimens) and risk for chronic disease and premature death. The overarching scientific priorities are (a) increasing understanding of the mechanisms underpinning vulnerability to unhealthy behavior patterns and (b) developing more effective behavior-change interventions. Advances in each of these areas are essential to improving U.S. population health, reducing health disparities, and curtailing spiraling health care costs. VCBH has made considerable progress in Phase 1 towards establishing a productive center of research excellence in this important area of biomedical research. VCBH currently consists of 20 UVM faculty members, highly accomplished external, internal, and community advisors, and collaborators from other IDeA states and beyond. The current faculty is multidisciplinary, evenly distributed across academic ranks, and highly productive, having published 118 articles in peer-reviewed journals and obtained $59,135,320 in additional external grant support during the initial four years of Phase 1 funding. We propose to continue prioritizing the mentoring of promising early-career faculty in Phase 2. We provided nine early-career faculty members with funded research projects and career-development support during Phase 1, using a multi-element mentoring plan that we will continue evaluating and refining during the proposed funding period. We propose continuing an Administrative Core that promotes effective communication, fiscal planning and oversight, supports a vibrant intellectual infrastructure, and directs and supports efforts to obtain external grant support. We have established two additional VCBH cores that we propose to continue, a Behavioral Economics and Intervention Sciences (BEIS) Core and a Collaboration, Dissemination, and Education (CDE) Core. The BEIS assists investigators with a decision-making and neuroimaging component to examine processes underpinning vulnerability to unhealthy behavior patterns, development of behavior-change interventions, and economic modeling of intervention cost-effectiveness. The CDE supports local, national, and international research collaborations, dissemination of new knowledge through a monthly lecture series, annual national conferences, annual Special Issues of the peer-reviewed journal Preventive Medicine, other publications, and educational efforts including seminars and workshops in behavior and health that are offered on the UVM campus and streamed live to collaborators and interested others. We are confident that continuing to develop and grow VCBH following this overall management plan will succeed in establishing a multidisciplinary center of research excellence in behavior and health with sustainable local, national, and international impact.