用于大脑中原位单细胞表达分析的空间基因组学-猫眼课题宝

用于大脑中原位单细胞表达分析的空间基因组学

批准号：

10082281

负责人：

Kirsten Frieda

金额：

$99.45万

依托单位：

SPATIAL GENOMICS, INC.

依托单位国家：

美国

项目类别：

财政年份：

2018

资助国家：

美国

项目状态：

已结题

起止时间：

2018-07-01 至 2022-08-31

来源：

https://reporter.nih.gov/project-details/10082281

关键词：

Address Adopted Attention BRAIN initiative Brain Cells Computer software Confocal Microscopy Custom Data Data Set Development Expression Profiling Familiarity Fluorescent in Situ Hybridization Future Gene Expression Gene Expression Profiling Genes Genomics Human Image In Situ Industry Laboratories Liquid substance Marketing Messenger RNA Methods Microscope Modeling Molecular Mus Nature Neurodegenerative Disorders Neurosciences Pattern Phase Production Publications RNA Research Research Personnel Running Safety Sampling Site Slice Specific qualifier value Standardization Technology Testing Tissues Training base brain cell brain tissue cell type commercialization experience experimental study gene panel instrument interest novel preservation prototype screening single-cell RNA sequencing touchscreen transcriptome transcriptomics user-friendly

项目摘要

项目成果

Kirsten Frieda的其他基金

相似基金

相关文献

中文摘要

翻译

总结 Spatial Genomics，Inc.正在将seqFISH技术商业化，基因在mRNA水平在单细胞中的空间信息保存。最近的进展使得有可能在组织中直接在单细胞中实现10，000个基因的多重化（Eng等， Nature 2019）。通过这项技术，可以在原位和空间发现新的细胞类型，组织可以在脑组织切片中直接识别和可视化。

英文摘要

SUMMARY Spatial Genomics, Inc. is commercializing seqFISH technology that can visualize thousands of genes at the mRNA level in single cells with spatial information preserved. Recent advances now make it possible to achieve 10,000 gene multiplexing in single cells directly in tissues (Eng et al., Nature 2019). With this technology, novel cell types can be discovered in situ and spatial organizations can be directly identified and visualized in brain tissue sections.

期刊论文(0)

专著(0)

科研奖励(0)

会议论文