Louisiana Clinical and Translational Science Center

项目总结/摘要 在美国，COVID-19在低收入和服务不足的人群中暴露了不成比例的健康负担 社会的在路易斯安那州，一些最大的健康和经济后果在我们的黑人中很明显。 社区.迫切需要在这些社区建立有效的检测战略， 秋冬病毒潮展开。路易斯安那州临床和转化科学（LA CaTS）中心提供 我们地区生物医学研究的重要基础设施和关键基础支持， 能够领导一个社区参与的测试研究项目，以确定COVID-19测试的差异 基于社区（教堂、社区中心和学校）和基于诊所的检测之间的比率 地点，并确定将增加在服务不足的黑人社区的测试吸收的方法， 南我们计划采用双管齐下的方法来解决这些问题。首先，我们将使用基于社区的 参与性研究方法，以确定不同国家SARS-CoV-2检测率的差异 在美国南部五个城市服务不足的黑人社区内的测试地点类型。我们将使用 一项多媒体运动，推广及进行从2，000名 成年人在1）医疗诊所，2）学校，3）社区中心和4）教堂（随机顺序）在五 已知社会经济地位低（SES）和黑人居民代表性高的邮政编码。的 主要结果将是在每种类型的测试地点进行的测试数量。我们将收集以下信息： 年龄、性别、种族、BMI、就业、健康的社会决定因素，使用SES总分来确定 测试率的重要相关因素。第二，我们将进一步发挥我们强大的综合实力， 与巴吞鲁日市长的健康城市倡议以及我们的洛杉矶CaTS社区合作 咨询委员会开展以社区为基础的重点小组活动，以获得关于 与测试准入有关的观念和态度以及影响这方面的潜在障碍。我们将使用这个 信息，以确定社区驱动的方法，有效地减少障碍， 在城市服务不足的黑人社区增加SARS-CoV-2检测的战略。结果 该项目将大大增加我们对导致COVID-19不成比例的因素的理解 这些得不到充分服务的人口的健康负担，并为制定减少 这些差异在所有服务不足的黑人社区。由此产生的数据将为公平部署 未来的病毒/流感测试和SARS-CoV-2疫苗。

Project Summary/Abstract In the US, COVID-19 has unveiled a disproportionate health burden in low income and underserved segments of society. In Louisiana, some of the greatest health and economic consequences are evident in our Black communities. There is an urgent need to establish effective testing strategies in these communities as the Fall/Winter virus surges unfold. The Louisiana Clinical and Translational Science (LA CaTS) Center provides the essential infrastructure and key foundational support for biomedical research in our region and is uniquely positioned to lead a community-engaged testing research project to determine differences in COVID-19 testing rates between community-based (churches, community centers, and schools) and medical clinic-based testing sites, and determine approaches that will increase uptake of testing in underserved Black communities in the South. We plan to address these issues using a two-pronged approach. First, we will use a community based participatory research approach to determine differences in SARS-CoV-2 testing rates across distinct types of test sites within five urban underserved Black communities in the American South. We will use a multimedia campaign to promote and conduct RT-PCR testing on salivary samples obtained from 2,000 adults at 1) medical clinics, 2) schools, 3) community centers, and 4) churches (in random order) within five ZIP codes with known low socioeconomic status (SES) and a high representation of Black residents. The primary outcome will be the number of tests performed at each type of test site. We will collect information on age, sex, race, BMI, employment, social determinants of health using an aggregate SES score to identify important correlates of testing rates. Second, we will further leverage our strong and well-integrated partnership with the Baton Rouge Mayor's Healthy City Initiative together with our LA CaTS Community Advisory Boards (CABs) to conduct community-based focus groups to obtain qualitative data about the perceptions and attitudes related to testing access and potential barriers affecting such. We will use this information to determine community-driven approaches that are effective in reducing barriers and create strategies to increase SARS-CoV-2 testing uptake in urban underserved Black communities. Results of this project will greatly increase our understanding of the factors that have led to a disproportionate COVID-19 health burden in these underserved populations and lay the groundwork for developing strategies to reduce these disparities in all underserved Black communities. Resulting data will inform the equitable deployment of future virus/flu testing and a SARS-CoV-2 vaccine.