Administrative Core

项目摘要 新型冠状病毒（COVID-19）加剧了美国各地的健康差距， 美国印第安人/阿拉斯加原住民（AI/AN）受到严重影响。亚利桑那 拥有世界上第三大 美国的AI/AN人口（超过350，000），是22个联邦承认的主权土著民族的家园。 与白人相比，亚利桑那州的AI/AN的健康危险因素患病率明显较高， 增加他们对COVID-19的易感性。AI/AN约占该州人口的4.6%，但 在报告了受害者种族和民族的情况下，占COVID-19死亡人数的19%。的长期目标 这项研究旨在开展社区参与的研究和外展活动，以提高对COVID-19的认识， 亚利桑那州AI/AN社区受COVID-19影响不成比例， 错误信息和不信任本行政补充文件的目标是建立有效的、文化上的 采取适当的策略，加强人工智能/人工智能社区参与预防和治疗新冠肺炎- 19，包括疫苗试验和未来的疫苗摄取。这项工作将由社区参与指导 该框架强调科学家和社区成员公平参与所有 研究的阶段。与母公司U 54 RCMI流域内的AI/AN社区合作： 西南健康公平研究合作组织（SHERC），我们的目标是：1）评估意识， 关于COVID-19疫苗试验和疫苗接种的知识、经验、担忧、态度和需求 亚利桑那州AI/AN社区的吸收; 2）开发和适应文化适当的教育 旨在提高对COVID-19疫苗试验的认识，减少错误信息， 增加医疗信任; 3）实施教育会议，评估教育的影响 关于提高认识、信任、自我效能以及参与意愿和意图的材料和战略 新型冠状病毒疫苗试验和未来的疫苗。迫切需要更好地解决 在亚利桑那州COVID-19疫情的关键时刻，AI/AN社区。知识来源于此 这项研究有可能提高人们对COVID-19疫苗试验的认识，并提高参与者的参与度。 试验中的AI/AN和未来的疫苗摄取。SHERC独特的地理和文化环境， 结合这一跨学科研究团队的经验和专业知识， 为成功而学习。

PROJECT SUMMARY The novel coronavirus (COVID-19) has exacerbated health disparities throughout the United States (US) and impacted American Indian/Alaska Native (AI/AN) populations in significant ways. Arizona has the third largest population of AI/AN in the US (over 350,000) and is home to 22 federally recognized sovereign Native nations. Compared with Whites, AI/AN in Arizona have a significantly higher prevalence of health risk factors that increase their susceptibility to COVID-19. AI/AN represent approximately 4.6% of the state’s population, yet account for 19% of COVID-19 deaths where race and ethnicity of victims is reported. The long-term goal of this study is to conduct community-engaged research and outreach to increase COVID-19 awareness and education among AI/AN communities in Arizona disproportionately affected by COVID-19 and to reduce misinformation and mistrust. The goal of this Administrative Supplement is to establish effective, culturally appropriate strategies to enhance participation of AI/AN communities in prevention and treatment of COVID- 19, including vaccine trials and future vaccine uptake. This work will be guided by a community engagement framework, which emphasizes equitable participation between scientists and community members in all phases of the research. In partnership with AI/AN communities in the catchment area of the parent U54 RCMI: The Southwest Health Equity Research Collaborative (SHERC), we aim to: 1) Assess awareness, knowledge, experiences, concerns, attitudes, and needs regarding COVID-19 vaccine trials and vaccination uptake among AI/AN communities in Arizona; 2) Develop and adapt culturally-appropriate educational materials and strategies designed to increase awareness of COVID-19 vaccine trials, decrease misinformation, and increase medical trust; and 3) Implement the educational session and evaluate the impact of educational materials and strategies on enhanced awareness, trust, self-efficacy, and willingness and intent to participate in COVID-19 vaccine trials and future vaccines. There is an urgent need to better address the concerns of AI/AN communities at this critical juncture of the COVID-19 pandemic in Arizona. Knowledge derived from this study has the potential to build awareness about COVID-19 vaccine trials and enhance participation among AI/ANs in the trials and future vaccine uptake. The unique geographical and cultural setting of SHERC, combined with the experience and expertise of this interdisciplinary team of investigators, well-positions the proposed study for success.