CORE 1: Administrative

该计划项目管理核心旨在通过多个PI提供科学的领导 内部和外部的领导层、指导委员会和咨询委员会。通过以下方式频繁开会 电话会议和面对面会议确保了该计划的顺利运行和协作性质。这个 计划项目于2012年首次设想，从那时起，该团队一直在合作，以带来 计划项目实现目标。 领导层由多重PI机制管理。玛丽安·贝里克博士，一位流行病学家 在黑色素瘤预防和生存领域工作了近30年的是Pi和Nancy博士的联系人 托马斯是一名皮肤病学家和分子流行病学家，两人都在一起工作了15年以上。 正在进行的大型黑色素瘤项目。指导委员会由项目负责人、 核心领导人和几个主要参与者：Marianne Berwick-项目一，Nancy Thomas-项目二， Eva Hernando-Monge-项目三、沈荣来-项目四、科林·贝格-项目四和 生物信息学核心，克劳斯·布萨姆-生物科学核心，艾琳·奥洛-生物科学核心，伊万·戈尔洛夫- 生物信息学核心，Christopher Amos-项目一和生物信息学核心，Marc Ernstoff-项目一。 指导委员会成员每周举行电话会议，并将继续 在可预见的未来，每隔一周见面一次。他们至少每年都会亲自见面，有时甚至会 一年中有好几次。内部咨询委员会由两名黑色素瘤肿瘤学家和实验室组成 研究-Paul Chapman和Stergios Moschos，生物统计学家-Venkat Seshan，实验室科学家 是甲基化研究的专家史蒂夫·别林斯基，以及皮肤病病理学家马库斯·博森伯格。我们会 提供资金时，请指定一个外部顾问委员会。它将由一名分子肿瘤学家，一名遗传学家， 一位免疫学家和一位表观遗传学专家。 行政核心将负责财政管理和赠款报告。它也将是 负责机构提供的临床数据的管理、协调和分发。 此外，它还负责项目之间的协调沟通以及与国家 癌症研究所。它还负责遵守所有机构、政府和NCI的法规 和政策。

This Program Project Administrative Core was designed to provide scientific leadership through the Multiple PI leadership, the Steering Committee and the Advisory Board, Internal and External. Frequent meeting by teleconference and in-person assures the smooth running and collaborative nature of the Program. The Program Project was first envisioned in 2012 and the team has been working together since then to bring the Program Project to fruition. The Leadership is managed by a Multiple PI mechanism. Dr. Marianne Berwick, an epidemiologist who has worked in the area of melanoma prevention and survival for almost 30 years is the contact PI and Dr. Nancy Thomas, a dermatologist and molecular epidemiologist, have both worked together for more than 15 years on large melanoma projects that are ongoing. The Steering Committee is made up of the Project Leaders, the Core Leaders and several key participants: Marianne Berwick – Project One, Nancy Thomas – Project Two, Eva Hernando-Monge – Project Three, Ronglai Shen – Project Four, Colin Begg – Project Four and Bioinformatics Core, Klaus Busam – Biospecimen Core, Irene Orlow – Biospecimen Core, Ivan Gorlov – Bioinformatics Core, Christopher Amos – Project One and Bioinformatics Core, Marc Ernstoff – Project One. The members of the Steering Committee have been meeting by teleconference weekly and will continue to meet every other week for the foreseeable future. They have met in person at least annually and sometimes several times in the year. The Internal Advisory Board consists of two melanoma oncologists with laboratory research – Paul Chapman and Stergios Moschos, a Biostatistician – Venkat Seshan, a laboratory scientist who is an expert in methylation studies – Steve Belinsky, and a dermatopathologist – Marcus Bosenberg. We will name an external advisory board when funded. This will be composed of a Molecular Oncologist, a geneticist, an immunologist and an epigenetics expert. The Administrative Core will be responsible for Fiscal management and grant reporting. It will also be responsible for management, harmonization and distribution of the clinical data provided by the institutions. Furthermore, it is responsible for the harmonious communication among the projects and with the National Cancer Institute. It is also responsible for compliance with all institutional, governmental and NCI regulations and policies.