Mays Cancer Center at UT Health SA

项目概要-质谱共享资源 质谱共享资源（MSSR）的目的是提供梅斯癌症中心（MCC） 成员和德克萨斯大学健康圣安东尼奥（UT健康SA）的研究人员与全面的，国家- 为蛋白质、代谢物和其他生物医学重要物质的表征和定量提供最先进的支持 分子的质谱分析。自1998年以来，MSSR一直是癌症中心的共享资源， 位于1，034 sq.英尺在UT健康SA的长（主）校园的两个实验室的空间。的 MSSR由UT Health SA和MCC共同管理。蛋白质组学是MSSR的主要焦点， 提供广泛的服务，包括分子量测定，蛋白质鉴定和相关 定量和蛋白质修饰位点的鉴定/定位。其服务范围包括： 多年来，随着大量NIH支持的新设备的购置， 仪器赠款和UT系统的资金。共享资源还提供咨询 调查的各个阶段以及对MCC调查员的培训。MSSR由Susan T执导。 温特劳布博士，自1998年以来Weintraub博士在利用质谱分析方面具有丰富的经验， 创新的研究，并担任了几个国家的领导职务，包括美国协会主席 用于质谱分析MSSR团队在使用质谱法解决 重要的癌症相关问题。在上一个供资期间，MSSR为31个同行评审资助的项目提供了服务。 MCC成员。它的同行评审资助MCC成员的年使用率平均为27%。

Project Summary—Mass Spectrometry Shared Resource The purpose of the Mass Spectrometry Shared Resource (MSSR) is to provide the Mays Cancer Center (MCC) members and University of Texas Health San Antonio (UT Health SA) investigators with comprehensive, state- of-the-art support for characterization and quantification of proteins, metabolites and other biomedically important molecules using mass spectrometry. The MSSR has been a Cancer Center Shared Resource since 1998 and is housed in 1,034 sq. ft. of space in two laboratories on the Long (main) campus of the UT Health SA. The MSSR is jointly managed by the UT Health SA and the MCC. Proteomics is the main focus of the MSSR, providing a wide range of services that include molecular mass determination, protein identification and relative quantification, and identification/localization of sites of protein modification. The scope of its service has expanded significantly over the years with the acquisition of new equipment supported by numerous NIH Instrumentation grants and by funds from the UT System. The Shared Resource also offers consultation at all stages of an investigation as well as training to MCC investigators. The MSSR has been directed by Susan T. Weintraub, Ph.D., since 1998. Dr. Weintraub has extensive experience in utilizing mass spectrometry for innovative research and served in several national leadership roles including President of the American Society for Mass Spectrometry. The MSSR team has exceptional expertise in the use of mass spectrometry to solve important cancer-related questions. During the last funding period, the MSSR serviced 31 peer-review funded MCC members. Its annual usage by peer-review funded MCC members averaged 27%.