SIREN Administrative Supplement

项目概要和摘要 本补充要求支持关键人员的努力，这将使坦普尔大学临床研究 创新急救护理临床试验网络战略中心（Temple-SIREN） 招募参与者参与紧急护理研究，并帮助在当地实施SIREN试验 和地区性的Temple-SIREN表演场地。请求提供补充支助，以维持业务 在SIREN第一个5年的正常供资结束和SIREN第二个5年开始之间。 中心的不间断支持将确保参与者成功入组正在进行的SIREN试验： ICECAP、BOOST-3和HOBIT。我们将继续支持这些试验的辅助研究：PRECICECAP 和Bio-BOOST。行政补充资金将使我们更好地实现具体目标 本项目Temple-SIREN奖的两个主要目标是：1）提供现场和项目管理 加快SIREN研究启动并优化Temple-SIREN的患者招募和方案依从性 2）建立一个区域性的生物医学研究人员系统，以竞争未来的NIH赠款， study.

Project Summary and Abstract This supplement requests support of effort for key individuals that will allow Temple University Clinical Research Hub for the Strategies to Innovate Emergency Care Clinical Trials Network (Temple-SIREN) to continue operations for recruiting participants into emergency care research and to help implement SIREN trials at local and regional Temple-SIREN performance sites. Supplemental support is requested to maintain operations between the end of regular funding for the first 5 years of SIREN and start of the second 5 years of SIREN. Uninterrupted support of the Hub will ensure successful enrollment of participants into the ongoing SIREN trials: ICECAP, BOOST-3, and HOBIT. We will continue to support the ancillary studies for these trials: PRECICECAP and Bio-BOOST at eligible sites. Administrative supplemental funding will allow us better fulfill the specific aims of the project. Two major aims of the Temple-SIREN award are to 1) to provide site and project management to expedite SIREN study start-up and to optimize patient recruitment and protocol adherence at Temple-SIREN sites and 2) develop a regional system of biomedical researchers to compete for future NIH grants and to study.