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Training in Signature Transdisciplinary Cardiovascular Sciences

Training in Signature Transdisciplinary Cardiovascular Sciences
标志性跨学科心血管科学培训
批准号:
10628014
负责人:
Ivor James Benjamin
金额:
$54.22万
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
未结题
起止时间:
2017-05-01 至 2027-06-30

项目摘要

项目成果

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中文摘要
翻译
项目摘要/摘要 这是我们的T32博士后项目的第一次续签(为期3年,要求维持我们的6年制 职位/年)威斯康星大学心血管医学院的MD、DOS、药学博士和博士 中心。在我们成功的基础上,36%的被任命人来自代表性不足的团体,100%的人来自 毕业生(n=5)获得NIH进一步资助(2个K99、K01、F32等),创新的新组成部分包括 多样化的领导力,更精致、更多样化的教师导师群体,新的学术课程,以及 与校园中心进行新颖的合作,以加强翻译科学。有强有力的制度支持 和心血管研究的卓越,我们利用多PI领导,最近更新了一项临床 和翻译科学奖,一个新的美国心脏协会战略重点研究 网络奖励和慈善支持,以资助实习生招募和丰富培训。董事们是 具有丰富管理经验的知名医生和科学家,以及30名基本 科学家和翻译研究人员充当导师。我们的培训计划是由一个高度 具有360度评估系统的集成式协作研究环境 围绕着我们的标志性项目,动脉粥样硬化方面的特定科学卓越领域, 血栓形成和血管生物学,2)心脏生物学和心力衰竭,3)精密心血管医学, (4)高血压。我们的计划强调旨在启动/保持独立的关键组件 研究生涯:1)3年支持(重新)拨款申请,2)个性化发展计划 (IDP),3)受保护的研究时间,4)多学科指导团队,5)核心能力培训, 以及6)为不从事传统职业的受训者提供工业/生物技术或科学联络职业选择 在学术界。严格的全国性选拔程序有助于我们多样化的学员选拔和团队 使用创新工具(例如,DISC®和职业道路评估)优化指导。Idp包括 进步责任的基本要素,跨多个翻译级别的协调, 与心血管和非心血管科学家的互动,近距离同行学习机会,具体 课程作业、研讨会和会议。我们的长期基准/目标是为超过50%的 博士后实习生在离开我们的项目后的3到5年内过渡到有竞争力的教师职位。 我们的中间基准包括出版物、演示文稿和拨款提交。以及 具有丰富经验的董事、执行委员会和外部咨询委员会 职业发展、领导力和指导培训补助金都提供项目监督和监督 实习生每6个月和12个月进步一次。总体而言,我们培训计划的最终目标是培训 下一代心血管科学家和医生,包括科学界代表性不足的群体 和医学,通过纳入广泛的、个性化的、支持性的和严格的培训机会。
英文摘要
PROJECT SUMMARY/ABSTRACT This is the first renewal for our T32 postdoctoral program (3-year duration, requesting to maintain our 6 positions/year) for MDs, DOs, PharmDs, and PhDs at the Medical College of Wisconsin’s Cardiovascular Center. Building on our successes with 36% of appointees from underrepresented groups and 100% of graduates (n=5) with further NIH funding (2 K99s, K01, F32, etc.), innovative new components include diversification of leadership, a refined, more diverse group of faculty mentors, a new academic course, and novel collaborations with campus centers to enhance translational science. With strong institutional support and excellence in cardiovascular research, we leverage multi-PI leadership, the recent renewal of a Clinical and Translational Science Award, a new American Heart Association Strategically Focused Research Network award, and philanthropic support to fund trainee recruitment and enrich training. The Directors are established physicians and scientists with extensive administrative experience who, along with 30 basic scientists and translational investigators, serve as mentors. Our training program is scaffolded by a highly integrated collaborative well-resourced research environment with a 360-degree evaluation system surrounding our Signature Programs, specific areas of scientific excellence in 1) atherosclerosis, thrombosis, and vascular biology, 2) cardiac biology and heart failure, 3) precision cardiovascular medicine, and 4) hypertension. Our program emphasizes critical components designed to launch/sustain independent research careers: 1) 3 years of support to enable grant (re)submissions, 2) individualized development plans (IDP), 3) protected research time, 4) multidisciplinary mentoring teams, 5) training in core competencies , and 6) industry/biotechnology or scientific liaison career options for trainees not pursuing a traditional career in academia. A rigorous nationwide selection process aids in our diverse trainee selection and team mentoring is optimized using innovative tools (e.g., DiSC® and career path assessments). The IDP includes foundational elements of progressive responsibility, coordination across multiple levels of translation, interactions with cardiovascular and non-cardiovascular scientists, near-peer learning opportunities, specific coursework, seminars, and conferences. Our long-term benchmark/goal is for more than 50% of our postdoctoral trainees to transition into competitive faculty positions within 3 to 5 years of exiting our program. Our intermediate benchmarks include publications, presentations, and grant submissio ns. Along with the Directors, an Executive Committee and External Advisory Committee that have extensive experience with career development, leadership, and directing training grants all provide program oversight and monitor trainee progress every 6 and 12 months. Overall, the ultimate goal of our training program is to train the next generation of cardiovascular scientists and physicians, including underrepresented groups in science and medicine, by incorporating broad-based, personalized, supportive, and rigorous training opportunities.
期刊论文(17)
专著(0)
科研奖励(0)
会议论文
Sustained Use of the Impella 5.0 Heart Pump Enables Bridge to Clinical Decisions in 34 Patients.
持续使用 Impella 5.0 心脏泵为 34 名患者提供了临床决策的桥梁。
DOI: 10.14503/thij-20-7260
发表时间: 2021
期刊: Texas Heart Institute journal
影响因子: 0.9
作者: [Nelson,DanielW, Sundararajan,Sakthi, Klein,Evan, Joyce,LyleD, Durham,LucianA, Joyce,DavidL, Mohammed,AsimA]
通讯作者: Mohammed,AsimA
DOI: 10.1080/07853890.2023.2269586
发表时间: 2023
期刊: Annals of medicine
影响因子: 4.4
作者: []
通讯作者:
Transgene-associated human growth hormone expression in pancreatic β-cells impairs identification of sex-based gene expression differences.
胰腺β细胞中转基因相关的人类生长激素表达损害了基于性别的基因表达差异的识别。
DOI: 10.1152/ajpendo.00229.2018
发表时间: 2019
期刊: American journal of physiology. Endocrinology and metabolism
影响因子: --
作者: [Stancill,JenniferS, Osipovich,AnnaB, Cartailler,Jean-Philippe, Magnuson,MarkA]
通讯作者: Magnuson,MarkA
Impaired microvascular reactivity in patients treated with 5-fluorouracil chemotherapy regimens: Potential role of endothelial dysfunction.
接受 5-氟尿嘧啶化疗方案治疗的患者微血管反应性受损:内皮功能障碍的潜在作用。
DOI: 10.1016/j.ijcha.2023.101300
发表时间: 2023-12
期刊: International journal of cardiology. Heart & vasculature
影响因子: --
作者: [Hammond ST, Baumfalk DR, Parr SK, Butenas ALE, Scheuermann BC, Turpin VG, Behnke BJ, Hashmi MH, Ade CJ]
通讯作者: Ade CJ
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