PREMISE: Pandemic Response Repository through Microbial and Immune Surveillance and Epidemiology

预提计划是一项积极的大流行病防范规划，目的是建立切实可行的免疫生物学对策储备，以加快全球对大流行病威胁的应对

PREMISE is a proactive pandemic preparedness program to establish a stockpile of tangible immunobiological countermeasures to accelerate the response to pandemic threats globally PREMISE assesses immune responses against known and novel viruses in targeted human populations PREMISE translates these data into diagnostic, therapeutic and prophylactic assets Deliverables: Reagent and data resources for early detection and diagnostic assays Monoclonal antibodies with potential for prevention and therapy Immunogens suitable for vaccine discovery and development Activities: Conduct genetic analysis of zoonotic reservoirs and symptomatic humans for pathogen discovery Develop high throughput, multiplexed serologic and cellular immune assays Identify antigen-specic and cross-reactive immune responses to known and novel viruses in strategically targeted cohorts Establish and expand in-country laboratory assay capabilities