Academic Pediatric Infectious Disease

摘要 华盛顿大学(UW)儿科传染病(PID)培训计划(TP)的目标 是培训未来的儿童传染病研究带头人。我们的TP(1)招聘人员经验丰富， 专职儿科医生和研究人员；(2)对他们进行分子、基因组、蛋白质组、生物信息学和 流行病学方法，以及(3)指导他们制定和领导独立的研究计划。我们 请求延长T32支持，每年培训四名学员进行研究。最初，每个儿科医生研究员 在西雅图儿童医院(SCH)的支持下，参加了为期12个月的临床培训(用于PID认证)。 随后，T32将为每个人提供为期2年的培训学院(TF)指导研究的支持，TF是 在各自研究领域的领导者，并在指导方面表现出色。鼓励学员和特遣部队处理项目 为理解和治疗儿科传染病和 生成K、R或其他奖励的初步数据。此外，受训者还可以接受说教和实践 关于人类和/或动物研究的联邦法规中的教育、补助金和手稿 准备工作，以及在学术界取得成功的策略。我们的课程包括一个有组织的过渡时间表 对于“K”系列NIH奖项，如果需要，我们部门将提供支持，以帮助学员过渡。我们的 自1981年以来，由NIH T32支持的UW-PID-FP已经培训了102名研究员，并一直保持着开发的记录 母婴健康研究带头人(图1，方案计划)。在过去的15年里，30名研究员 成功完成我们的TP，1人转到不同的TP，1人退出培训，7人是现任研究员， 1名即将上任的研究员将于2022年7月开始工作。截至2022年5月，在过去15年的30名TP毕业生中， 15人(50%)获得了K级证书。在5年前完成TP课程的毕业生中(因此 第一阶段将进展到NIH R级资助)，6/20(30%)已获得R。生物医学研究 仍然是过去15年19/30(63%)毕业生的主要关注点：16个领先的学术实验室(PI R，K或基金会赠款)，1是拥有内部资金的政府机构的首席研究员，1是 工业研究员，1人是大学生物学教授，教授本科生并进行研究。 其余11/34人(37%)包括：在学术医院参加的8名临床医生教育人员 研究人员和3名临床传染病专家。我们现有的7名研究员和7月新加入的1名研究员 2022年，5人提交了≥1申请国家卫生研究院、政府和/或基金会拨款；2人获得奖励，1人 等待获奖通知，还有2份申请待决。在我们现有的研究员和应届毕业生中(N=38) 在过去的15年里，有6人(16%)是代表不足的少数族裔(URM)或来自NIH定义的弱势群体 健康科学方面的团体。2022年，两名研究员将完成奖学金，两人都将继续担任威斯康星大学的教员。

ABSTRACT The objective of our University of Washington's (UW) Pediatric Infectious Diseases (PID) Training Program (TP) is to train future research leaders in infectious diseases of children. Our TP (1) recruits experienced and committed pediatricians and researchers; (2) trains them in molecular, genomic, proteomic, bioinformatic, and epidemiologic methods, and (3) mentors them to develop and lead an independent research program. We request the renewal of T32 support to train four trainees in research annually. Initially, each pediatrician fellow engages in 12 months of clinical training (for PID certification), supported by Seattle Children's Hospital (SCH). Subsequently, the T32 will support each for 2 years of mentored research by Training Faculty (TF) who are leaders in their areas of research and excel at mentorship. Trainees and TF are encouraged to tackle projects that contribute novel and critical insights into understanding and treating pediatric infectious diseases and generate preliminary data for a K, R, or other awards. In addition, trainees receive didactic and hands-on education in the federal regulations governing research with humans and/or animals, grant and manuscript preparation, and strategies to succeed in academia. Our curriculum includes a structured timeline to transition to “K”-series NIH awards, and if needed, our department extends support to assist trainees in this transition. Our NIH T32-supported UW-PID-FP has trained 102 fellows since 1981, with a consistent record of developing research leaders in Maternal-Child Health (Figure 1, Program Plan). During the past 15 years, 30 fellows have successfully completed our TP, 1 transferred to a different TP, 1 withdrew from training, 7 are current fellows, and 1 incoming fellow will begin in July 2022. As of May 2022, of the 30 TP graduates from the past 15 years, 15 (50%) have been awarded Ks. Of the graduates completing our TP more than 5 years ago (and therefore at the stage one would progress to NIH R-level funding), 6/20 (30%) have received Rs. Biomedical research continues to be a primary focus of 19/30 (63%) graduates from the last 15 years: 16 lead academic labs (PIs of R, K or foundation grants), 1 is a lead researcher within a government institutions with intramural funds, 1 is an industry researcher, and 1 is a university biology professor teaching undergraduates and performing research. The remaining 11/34 (37%) include: 8 clinician educators at academic hospitals where they participate in research, and 3 clinical infectious disease specialists. Of our 7 current fellows and 1 new fellow entering in July 2022, 5 have submitted ≥1 applications for NIH, government, and/or foundation grants; 2 received awards, 1 awaits notice of award, and 2 have pending applications. Among our current fellows and recent graduates (N=38) from the past 15 years, 6 (16%) are under-represented-minorities (URM) or from NIH-defined disadvantaged groups in health sciences. In 2022, two fellows will complete fellowship and both will continue as faculty at UW.