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International Research in Thailand

International Research in Thailand
泰国的国际研究
批准号：
7732717
负责人：
Steven Holland
金额：
$5.52万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/7732717
关键词：
Anonymous TestingAsiansAutoantibodiesBlood BanksDiseaseEnrollmentGoalsHistoplasmosisInterferon Type IIInternationalLaboratoriesLymphocyte CountMycobacterium InfectionsOpportunistic InfectionsPatientsPlasmaPopulationProtocols documentationReportingResearchResearch Ethics CommitteesResearch InfrastructureSamplingSeriesThailandUnited StatesUnited States National Institutes of Healthcytokine

项目摘要

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中文摘要
翻译
我们之前已经证明，泰国北方该人群的患者中存在干扰素γ的自身抗体，而血库捐献者不存在这些自身抗体。我们花了去年的时间在泰国制定了执行该项目的方案和基础设施，现在已经准备好在收到IRB的最终批准后立即招募。我们已经开发了当地实验室支持，以获得适当的淋巴细胞计数和血浆样本以及细胞因子刺激物，并将其运送至NIH进行分析。
英文摘要
We have previously shown that autoantibodies to interferon gamma exist in patients in this population in northern Thailand, and that blood bank donors do not have these autoantibodies. We have spend the last year developing the protocol and infrastructure in Thailand to execute this project, which is now ready to enroll as soon as the final IRB approvals are received. We have developed the local laboratory support to obtain appropriate lymphocyte counts and plasma samples and cytokine stimulations for shipment to the NIH for analysis.
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