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中文摘要
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描述(由申请人提供):钩端螺旋体病已成为发展中国家和发达国家的全球重要传染病威胁。近年来,该领域取得了快速进展,发表了四个完整的钩端螺旋体基因组序列,发表了基于微阵列和蛋白质组学的研究,并将现代遗传学和免疫学纳入宿主-病原体相互作用的实验阐明。国际钩端螺旋体病学会第六次会议将于2009年9月21日至24日在印度科钦举行。会议的目的是介绍钩端螺旋体和钩端螺旋体病的多学科和不同方面,以将实验室进展转化为更好的预防和治疗方法。讨论的主题将包括以下内容:钩端螺旋体病的全球流行病学和疾病负担,钩端螺旋体基因组学和蛋白质组学,分子和细胞发病机制,宿主反应和保护性免疫机制,以及疫苗开发。与会者将包括该领域的国际专家以及来自美国、亚洲、澳大利亚、欧洲和非洲的博士后和研究生学员。主旨发言者将包括在外地的常设和新的调查员。请拨的资金将用于支付受训人员的旅费和住宿费。将通过美国和国际组织发出对受训人员摘要的呼吁,并将努力针对最近发表的论文的高级和第一作者以及与钩端螺旋体病相关的NIH赠款的主要研究者。学员将通过提交一份研究摘要来竞争,要求资助旅行和出席会议。摘要将由ILS总裁和本R13赠款的PI任命的委员会选择支持。选择因素将主要基于提交的摘要的质量,沿着地理,性别,代表性不足的少数民族和社会经济多样性。会议成果将由与会者,特别是受训人员,通过同行评审的出版物进行评估,包括新的赠款支持和受训人员职业发展等国际合作努力得到加强。
英文摘要
DESCRIPTION (provided by applicant): Leptospirosis has emerged as a globally important infectious disease threat in both developing and developed countries. Rapid advances in the field have taken place in recent years, with publication of four complete Leptospira genome sequences, publication of microarray and proteomics-based research, and the integration of modern genetics and immunology into experimental elucidation of host-pathogen interactions. The Sixth meeting of the International Leptospirosis Society will take place in Cochin, India September 21-24, 2009. The purpose of the meeting is to present multidisciplinary and diverse aspects of Leptospira and leptospirosis towards the translation of laboratory advances to better methods of prevention and treatment. Topics of discussion will include the following: global epidemiology of leptospirosis and burden of disease, Leptospira genomics and proteomics, molecular and cellular pathogenesis, mechanisms of host response and protective immunity, and vaccine development. Participants will include international experts in the field, and postdoctoral and graduate trainees from the United States, Asia, Australia, Europe and Africa. Keynote speakers will include established and new investigators in the field. Funds requested will used to support trainee travel and accommodations. A call for trainee abstracts will be sent through US and international organizations, and efforts to target trainees will be made to senior and first authors of recently published papers and Principal Investigators of leptospirosis-related NIH grants. Trainees will compete by submitting a research abstract requesting funding to support travel and attendance at the meeting. Abstracts will be selected for support by a committee appointed by the ILS president and the PI of this R13 grant. Selection factors will be primarily based on the quality of the submitted abstract, along with geographic, gender, underrepresented minority and socioeconomic diversity. Outcome of the meeting will be assessed by peer-reviewed publication by participants, particularly trainees, demonstrated enhancement of international collaborative efforts including new grant support, and trainee career advancement.
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Predicting Risk of Human Leptospiros by Environmental Surveillance
  • 批准号:
    9820811
  • 项目类别:
  • 资助金额:
    $33.14万
  • 财政年份:
    2018
  • 负责人:
    Joseph M. Vinetz
  • 依托单位:
Draft
Addressing the Global Burden of Leptospirosis in Two Endemic Countries
Predicting Risk of Human Leptospiros by Environmental Surveillance
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