Home-Based Lithium Level Testing for Bipolar Patients
Home-Based Lithium Level Testing for Bipolar Patients
批准号:
7922943
负责人:
KUMAR SUBRAMANIAN
金额:
$18.36万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-30 至 2011-09-29
关键词:
Biological AssayBiosensorBipolar DisorderBlood BanksBlood specimenBody FluidsBuffersCaringCharacteristicsChronic DiseaseCollaborationsComplexDetectionDevelopmentDisadvantagedDoseDrug MonitoringFamilyFeedbackGlucoseGoalsHealth ProfessionalHome environmentIon-Selective ElectrodesLaboratoriesLaboratory ProceduresLiquid substanceLithiumLithium CarbonateLithonateManicMicrofluidicsModelingMonitorNamesPatientsPerformancePhasePhotometryPlasmaReagentReproducibilityResearchRunningSamplingScheduleSelf ManagementSerumSpecificitySpecimenSpectrum AnalysisSystemTestingTherapeuticTimeUrineValidationWeightabsorptionbasedesignmetermethod developmentperformance testsprototyperesearch studyresponsetoolusability
中文摘要
项目总和
其专有名称包括Eskalith、Lithane、Lithonate、Lithobid和
另一些则以碳酸锂的形式给药,用于治疗躁郁症。
精神障碍(BD)、躁狂和躁郁症。锂的一个缺点是
治疗范围窄(0.4-1.2 mmol/L),需要治疗药物
监控。锂在血清、血浆、尿液或其他体液中的锂浓度
通过火焰发射光度法、原子吸收光谱法测定
或使用离子选择电极的电化学方法。血清分析,最有用的
用于锂监测的样品最常见的是通过自动量化
分光光度分析。然而,实验室程序复杂且时间长。
在消费。随着慢性病自我管理模式的发展,有越来越多的
需要为患者提供监测和管理其护理的工具。一个家-
基于锂水平的测试将为BD患者及其家人提供工具
定期监测他们的锂水平,并根据情况调整治疗
由他们的健康专家指导。
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项目叙事
随着慢性病自我管理模式的发展,人们越来越需要
为患者提供监控和管理其护理的工具。一种家用锂
Level测试将为BD患者及其家人提供工具来监控他们的
定期调整锂水平,并根据其指示相应调整治疗
健康专业人士。
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英文摘要
PROJECT SUMIVIARY
Lithium whose proprietary names include Eskalith, Lithane, Lithonate, Lithobid and
others, is administered as lithium carbonate and used for treatment of the bipolar
disorders (BD), mania, and manic-depressive illness. A disadvantage of lithium is the
narrow therapeutic range (0.4 -1.2 mmol/L), which necessitates therapeutic drug
monitoring. The concentration of lithium in serum, plasma, urine, or other body fluids
have been determined by flame emission photometry, atomic absorption spectroscopy
or electrochemically using ion-selective electrode. Serum analysis, the most useful
specimen for lithium monitoring is most commonly quantified by automated
spectrophotometric assay. However, the laboratory procedures are complex and time
consuming. As chronic disease self-management models evolve, there is an increasing
need to provide patients with the tools to monitor and manage their care. A home-
based lithium level test would provide BD patients and their families with the tools to
monitor their lithium levels on a regular basis and adjust treatment accordingly as
directed by their health professional.
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PROJECT NARRATIVE
As chronic disease self-management models evolve, there is an increasing need to
provide patients with the tools to monitor and manage their care. A home-based lithium
level test would provide BD patients and their families with the tools to monitor their
lithium levels on a regular basis and adjust treatment accordingly as directed by their
health professional.
V^^*7
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