Training Program in Integrative Membrane Biology

描述（由申请人提供）：综合膜生物学培训计划（TPIMB）旨在培养生物膜生物学，生物物理学和生理学的博士生。现在是它的第三个十年，TPIMB继续在马里兰大学医学院（DM SoM）的细胞和系统生物学界面的跨学科培训的努力，通过关注细胞膜和胞内膜在介导和整合细胞功能及其与环境的相互作用中的作用。该计划的指导思想是，研究膜生物物理学和生理学，以及基于膜的信号级联，可以为健康和患病状态下的细胞和组织的生物学提供独特的见解。TPIMB的教师目前有40人，资金充足，高度互动，致力于指导学生学习与膜生物学相关的广泛学科。培训师是根据他们的兴趣、外部支持和对指导的承诺来选择的。学员也会根据他们的兴趣、本科成绩、标准化考试成绩、推荐信和以前的研究经验来选择。学生必须修习一系列关于膜生物化学和生物物理学的课程，以及关于膜缺陷与人类疾病之间的联系的课程，以及研究伦理学的课程。他们还学习细胞和系统生理学、药理学或神经科学的入门和/或高级课程。现在还需要开设一门新的强化核心课程，即细胞和分子生物学，这是UM SoM当前研究生教育重组的一部分。学员定期参加以学生为中心的活动，如研讨会、月度聚会和年度静修。澳大管理学院通过对教师工资、学生额外津贴和TPIMB日常活动的资助，慷慨地支持这个项目。目前美国国立卫生研究院的资金支持7名受训者，但许多人在没有支持的情况下跟随我们的课程并参加我们的活动。我们在研究生培训方面的努力有所增加，最近招聘的成功，以及澳大管理学院联邦资金的大幅增加，都表明受资助职位数量的增加是合理的。在持续和加强的支持下，TPIMB的教师和学生可以继续带头努力，在UM SoM整合细胞和系统生物学的培训

DESCRIPTION (provided by applicant): The Training Program in Integrative Membrane Biology (TPIMB) is designed to train predoctoral students in the biology, biophysics, and physiology of biological membranes. Now in its 3rd decade, the TPIMB continues to lead the effort in interdisciplinary training at the interface of cell and systems biology at the University of Maryland School of Medicine (DM SoM), by focusing on the role of the cell membrane and intracellular membranes in mediating and integrating the functions of cells and their interactions with the environment. The program is guided by the idea that studies of membrane biophysics and physiology, and of membrane-based signaling cascades, can provide unique insights into the biology of cells and tissues, in both healthy and diseased states. The faculty of the TPIMB, now numbering 40 individuals, are well funded, highly interactive, and devoted to mentoring students studying a broad range of subjects related to Membrane Biology. Trainers are selected for their interests, extramural support, and commitment to mentoring. Trainees are also selected based on their interests, as well as undergraduate records, standardized test scores, recommendations, and previous research experience. Students are required to take a series of courses on membrane biochemistry and biophysics, and on links between membrane defects and human diseases, as well as a class in research ethics. They also take introductory and/or advanced courses in cellular and systems Physiology, Pharmacology, or Neuroscience. A new intensive core course in Cell and Molecular Biology, devised as part of the current restructuring of graduate education at UM SoM, is now also required. Trainees participate regularly in student-oriented activities, such as seminars, monthly get-togethers, and an annual retreat. The UM SoM supports this program generously through contributions to faculty salary, additional stipends for students, and funds for the TPIMB's regular activities. Current NIH funding supports 7 trainees but leaves many following our curriculum and taking part in our activities without support. The growth of our graduate training efforts, successes in recent recruitment, and the large jump in federal funding at the UM SoM suggest that an increase in the number of funded positions is justified. With continued and enhanced support, the faculty and students in the TPIMB can continue to spearhead the effort to integrate training in cell and systems biology at the UM SoM