MBRS SCORE Program at Texas A&M University-Kingsville

德克萨斯A&M大学金斯维尔分校的MBRS评分计划包括以下主要目标：(1)为TAMUK的适当生物医学研究环境建立和提供支持；(2)提供适当的基础设施，使参与研究人员能够检查生物医学研究的关键方面；以及(3)提供关于生物医学相关性和重要性问题的大量和重要的数据和信息。 五项提案是以前资助的项目，涉及细胞凋亡、母体应激对免疫系统的影响、神经遗传学、毒液去整合素作用和视神经再生。十项建议是新提交的，包括细菌基因簇的功能分析、禽流感病毒亚型的监测、基于转座子的蚊子转基因、卵巢基因表达的转录调控、黄体组织发育和不孕、维生素B6衍生物介导的缺血性心脏病的缓解、蛋白质组学和质谱学的方法学、生殖内分泌学、柑橘衍生化合物在骨质疏松症中的作用，以及高中生滥用药物的健康后果。 这十个新项目，加上之前资助的五个项目，将支持七个不同系的研究，并为参与的教员提供理想的机会来扩大和加强他们的个人研究计划。研究人员个人的研究目标也将为在生物医学研究的关键方面培训本科生和研究生提供极好的机会，并为未来的生物医学研究职业生涯做好适当的准备。

The MBRS SCORE program at Texas A&M University-Kingsville consists of the following primary objectives: (1) establish and provide support for an appropriate biomedical research environment at TAMUK; (2) provide a suitable infrastructure that permits participant investigators to examine key aspects of biomedical research; and (3) provide substantial and significant data and information regarding questions of biomedical relevance and importance. Five proposals are previously funded projects encompassing apoptosis, maternal stress effects on the immune system, neurogenetics, venom disintegrin action, and optic nerve regeneration. Ten proposals are new submissions and encompass functional analysis of a bacterial gene cluster, surveillance of avian influenza virus subtypes, transposon-based transgenesis in mosquitoes, transcriptional regulation of ovarian gene expression, luteal tissue development and infertility, vitamin B6 derivative-mediated attenuation of ischemic heart disease, methodologies in proteomics and mass spectrometry, reproductive endocrinology, citrus-derived compounds in osteoporosis, and health consequences of substance abuse among high school students. Together these ten new projects, in addition to the five previously funded projects, will support research in seven different departments and provide ideal opportunities for the participant faculty to expand and enhance their individual research programs. The research goals of the individual investigators will also provide excellent opportunities for the training of undergraduate and graduate students in key aspects of biomedical research as well as suitable preparation for future careers in biomedical research.