Micreobiology and Animal Resources Core Laboratory

NERCE CORE A：微生物学和动物资源核心实验室，Andrew Onderdonk，博士， 哈佛医学院。 核心A实验室的总体目标是提供基础设施、行政支持、科学 BSL-2/ABSL-2实验室和动物设施的设备和人员，用于培训和研究 A、B和C类代理。这一设施包括获得豁免和选定的试剂菌株、实验室 用于访问调查人员的空间，以及用于实验前培训的生物安全和实验室设备 在核心A BSL-3/ABSL-3选择试剂实验室和动物设施工作。核心的具体目标 培训NERCE科学家和技术人员正确使用BSL-3/ABSL-3设施，并 提供训练有素的科学工作人员，使用A、B和C类优先事项支持调查人员进行研究 病原体。核心A实验室的一个基本的具体目标是准备和充分表征Master 为所有NERCE调查人员提供精选试剂和豁免菌株的种子批次库存，并增加 与NERCE赞助的科学家和NERCE核心实验室的合作研究活动。AS 作为我们总体任务的一部分，核心A实验室参与A类、B类、 和C生物，针对新出现的感染进行产品开发和临床干预 疾病威胁。在更大的社区内，Core A还通过LRN计划提供支持，以 马萨诸塞州国家实验室研究所和SLI要求的其他机构，作为第一个参与 可能发生的BT事件的响应者。核心A实验室通过一个 在整个新英格兰地区的其他机构和科学家的外展计划。

NERCE Core A: Microbiology and Animal Resources Core Laboratory, Andrew Onderdonk, Ph.D., Harvard Medical School. The overall goal of the Core A laboratories is to provide the infrastructure, administrative support, scientific equipment and personnel for a BSL-2/ABSL-2 laboratory and animal facility for training and research with category A, B and C agents. This facility includes access to exempt and select agent strains, laboratory space for visiting investigators, and bio-safety and laboratory equipment for training prior to experimental work in the Core A BSL-3/ABSL-3 Select Agent laboratory and animal facility. Specific aims for the Core are to train NERCE scientists and technical personnel in the proper use of BSL-3/ABSL-3 facilities and to provide trained scientific staff to support investigators with research using Category A, B and C priority pathogens. An essential specific aim for the Core A laboratory is to prepare and fully characterize master and seed lot stocks of select agents and exempt strains for all NERCE investigators and to increase collaborative research activities with NERCE sponsored scientists and across NERCE core laboratories. As part of our overall mission, the Core A laboratory participates in translational research with Category A, B, and C organisms directed at development of products and clinical interventions for emerging infectious disease threats. Within the greater community, Core A also provides support through the LRN program to the Massachusetts State Laboratory Institute and others, as requested by the SLI, involved as first responders for possible BT events. The Core A laboratory promotes the use of facilities through an outreach program to other institutions and scientists throughout the New England region.