Research Project

项目概述：尽管提供了更多有益的筛查测试，但在少数族裔和其他医疗服务不足的人群中，儿童权利公约的不成比例的负担仍然存在。为了解决这一差距，我们提出了一种创新的基于理论的教育干预措施，在联邦合格的卫生中心和卫生部门诊所提供，以提高患者对结直肠癌筛查(CRC)的认识，促进患者与提供者对结直肠癌筛查的讨论，并增加平均风险中对结直肠癌的吸收。 个人。我们建立在已建立的社区-学术伙伴关系和以社区为基础的参与性研究框架的基础上，以此为基础开展名为“结直肠癌意识、研究、教育和筛查”(CARE)的两阶段项目。第一阶段(第1年)的目标是设计和制作一个CARE工具包，其中包括一本DVD和Photoonovella小册子、放映就绪卡和提醒明信片，旨在为各种医疗服务不足的人群服务。共有107名个人将参加 这是形成性研究的一部分，使用健康素养框架作为开发教育工具包的基础。在第11阶段(第2-5年)，以社区为基础的前瞻性、纵向、随机干预研究的目标是：评估CARE工具包与标准手册干预(SI)对CRCs摄取的有效性；评估预防健康模型变量是否中介干预效果；以及检验成本效益。在这一阶段，总共420名年龄在50-75岁的男性和女性将被招募，并被随机分为CARE条件组或SI组(每组210人)。作为干预的一部分，两组都将接受免费的免疫化学粪便潜血检测(1-FOBT)试剂盒。I-FOBT和总体(任何测试) 筛查摄取率将在12个月后进行评估，并在不同条件下进行比较。预计CARE干预将与更大的筛查摄取率(FOBT和其他筛查)和SI条件下的成本效益相关。将使用多变量回归分析来评估与干预效果相关的因素。

Project Summary: The disproportionate burden of CRC persists among racial-ethnic minorities and other medically underserved populations despite increased availability of beneficial screening tests. To address this gap, we propose an innovative theory-based educational intervention delivered in federally qualified health centers and health department clinics to improve patient awareness about colorectal cancer screening (CRCS), facilitate patient-provider discussion of CRCS, and increase uptake of CRCS among average risk individuals. We build on our established community-academic partnerships and the community-based participatory research framework as the foundation for a two-phase project entitled "Colorectal Cancer Awareness, Research, Education and Screening" (CARES). The aim of Phase 1 (year 1) is to design and produce a CARES toolkit consisting of a DVD and photonovella booklet, screening readiness card, and reminder postcard intended for a diverse medically underserved population. A total of 107 individuals will take part in the formative research, which uses a health literacy framework as a basis for developing the educational tool kit. In Phase 11 (Years 2-5), the aims ofthe prospective, longitudinal, randomized communitybased intervention study are to: assess efficacy of CARES tool kit vs. a standard brochure intervention (SI) on CRCS uptake; assess whether Preventive Health Model variables mediate intervention effects; and examine cost-effectiveness. In this phase, a total of 420 men and women aged 50-75 years, will be recruited and randomized to either the CARES condition or SI (210 in each arm). Both groups will receive free immunochemical fecal occult blood test (1-FOBT) kits as part of the intervention. I-FOBT and overall (any test) screening uptake will be evaluated at 12 months and compared between conditions. It is expected that the CARES intervention will be associated with greater screening uptake (FOBT and other screening) and cost effectiveness that the SI condition. Multivariable regression analysis will be used to assess factors associated with intervention effects.