Training Program in Bioinformatics

描述（由申请人提供）：这是一份关于更新和发展密歇根大学（UM）生物信息学培训计划（BTP）的提案，该计划目前在密歇根大学计算医学和生物信息学中心（CCMB）内每年资助6个培训生名额，为期2-3年的博士前培训。BTP是一个跨学科的生物信息学和计算生物学研究生培训项目，吸引了来自医学院、工程、文学、科学和艺术学院（LS&A；包括数学系、统计学、化学系和物理系）、公共卫生学院、药学院和信息学院的教师。BTP的目标是通过严格的课程和博士前培训经验，培养学生在生物信息学和应用计算生物学方面的能力，同时从事具有很强的“驱动生物学问题”（DBP）应用的前沿合作研究，通常导致BTP学员具有很强的T1转化研究方向。BTP论文培训采用“双导师”方法，结合定量/计算和DBP应用元素。美国国立卫生研究院国家综合生物医学信息学中心（NCIBI）、癌症生物信息学、蛋白质组信息学活动和CTSA生物医学信息学项目都获得了全国的认可，对我们的学员和教师来说是一个天然的磁石。自2001年成立以来，BGP已发展到38名博士生和6名硕士，其中17名博士和14名硕士学位。如今，BTP项目已进入第五个年头，目前已有13名学生获得了BTP项目的支持，预计本学年将迎来首批3名毕业生。更新UM BTP将使我们能够在这一高度专业化的领域培养有前途的学生，这些学生将发展必要的技能和知识，在学术界、工业界和政府的基础和应用研究领域开展成功和独立的职业生涯。CCMB、BGP和BTP都非常积极地与全国各地的少数民族机构研究中心（RCMI）项目机构合作，建立健全的少数民族招生渠道。密歇根大学对生物信息学和计算生物学的机构支持非常强大，为BTP在拟议的5年期间乃至可预见的未来蓬勃发展奠定了稳定的基础。

DESCRIPTION (provided by applicant): This is a proposal to renew and grow the University of Michigan (UM) Bioinformatics Training Program (BTP), which currently funds 6 trainee slots/year for 2-3 years of pre-doctoral training, within our University of Michigan-wide Center for Computational Medicine and Bioinformatics (CCMB). The BTP is an interdisciplinary graduate training program in bioinformatics and computational biology, drawing faculty from the School of Medicine, College of Engineering, Literature, Sciences and the Arts (LS&A; Including the Departments of Mathematics, Statistics, Chemistry, and Physics), the School of Public Health, the College of Pharmacy, and the School of Information. The goal of the BTP is to train students in bioinformatics and applied computational biology by engaging them in a rigorous curriculum and pre-doctoral training experience, all the while engaging in cutting-edge collaborative research featuring a strong "driving biological problem" (DBP) application, often leading BTP trainees to have a strong T1 Translational Research orientation. The BTP dissertation training utilizes a "dual-mentor" approach, which combines quantitative/computational and DBP application elements. The UM-based NIH National Center for Integrative Biomedical Informatics (NCIBI), cancer bioinformatics, proteome informatics activities, and CTSA Biomedical Informatics Program have all achieved national recognition, and are a natural magnet for our trainees and faculty. Since its inception in 2001, the BGP has now grown to 38 Ph.D. students and 6 MS, with 17 Ph.D. and 14 MS degrees conferred. Now in its fifth year, the BTP has now contributed to the support of 13 of these students, with the its first 3 graduates expected this academic year. Renewing the UM BTP will enable us to sustain our ability to train promising students in this highly specialized domain who will develop the skills and knowledge necessary to launch successful and independent careers in basic and applied research in academia, industry, and government. The CCMB, BGP, and the BTP are all very actively building a robust minority recruitment pipeline in partnership with the Research Centers for Minority Institutions (RCMI) program institutions across the nation. Institutional support for bioinformatics and computational biology at the U-M is very strong, forming a stable base for the BTP to thrive in this proposed 5-year period and beyond into the foreseeable future.