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Genomics Core

Genomics Core
基因组学核心
批准号：
8935694
负责人：
Eugene Wei-Ming Yeo
金额：
$14.34万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8935694
关键词：
AstrocytesAutistic DisorderAwarenessBiologicalBiological AssayCellsCellular AssayClassificationClustered Regularly Interspaced Short Palindromic RepeatsCollaborationsCommunitiesConsultCustomDataDevelopmentEngineeringFloorGene ExpressionGene Expression ProfileGene Expression ProfilingGenesGenomicsHousingHumanIndividualInstitutesInstitutionKaryotype determination procedureKnowledgeLaboratoriesLibrariesMeasuresMedicineMethodsMolecular ProfilingNeurogliaNeuronsPatternPopulationPreparationProceduresPromoter RegionsProtocols documentationQuality ControlRNARegenerative MedicineResearch SupportRunningServicesStem cellsSystemTechniquesTechnologyTrainingUniversitiesValidationVariantbasebiosignaturedensitydesigndigitalembryonic stem cellempoweredexomegenome analysisgenome editinginduced pluripotent stem cellinnovationmembernew technologynext generation sequencingnovel strategiespre-clinicalresearch studysingle cell analysistranscriptome sequencing

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中文摘要
翻译
项目摘要 科帕卡巴纳基因组核心将提供创新、可靠和透明的服务， 新技术，以使项目能够实现其个别和总体目标，并传播新的 由项目为更广泛的社区开发的工作流程和分析。具体地说，基因组学核心 将使项目1、2和3能够推进验证基因组编辑的质量控制指标 技术，识别用于大脑皮层V层神经元和星形胶质细胞分类的稳健RNA特征 并提供高质量的单细胞RNA-SEQ数据，并向社区传播所有这些分析。
英文摘要
Project Summary The COPACABANA Genomics Core will provide innovative, reliable and transparent services using innovative new technologies to enable the Projects to accomplish their individual and overall aims and to disseminate new workflows and assays that are developed by Projects to the wider community. Specifically, the Genomics Core will enable Projects 1, 2 and 3 in advancing the quality control metrics for validating genome-editing technologies, identify robust RNA signatures for classification of cortical layer V neurons and astroglial cells and to provide high-quality single-cell RNA-seq data and disseminate all these analyses to the community.
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