Integrative and Multidisciplinary Pain and Aging Research Training

 描述(由申请人提供)：正如医学研究所(IOM)最近的一份报告所详细说明的那样，慢性疼痛是一个主要的公共卫生问题，影响着1亿美国成年人，每年花费超过5000亿美元。衰老会增加慢性疼痛的风险，有一半的老年人报告持续或反复疼痛，而衰老与疼痛相关的生理和心理社会功能的丧失更大。目前关于疼痛和衰老的知识令人惊讶地有限，该领域未来的进展取决于是否有训练有素的科学家，他们了解衰老和疼痛的临床前和临床研究方法。目前，NIH资助的T32项目还没有专门用于疼痛和衰老方面的培训。为了解决这一未得到满足的需求，我们建议开发一个新的博士后培训计划：综合和多学科疼痛与衰老研究培训(IMEPARE)计划。传授计划的总体目标是培养杰出的独立研究人员，能够维持富有成效的临床和转化性研究生涯，解决与年龄相关的疼痛体验变化背后的生物-心理-社会机制和/或设计临床干预措施，以缓解老年人的急性和慢性疼痛。为了实现这一总体目标，这一新的疼痛和衰老研究博士后培训计划的具体目标是：1)招募和培训有前途的初级研究人员，以进行疼痛和衰老方面的机械和临床相关的翻译研究；2)实施综合教学和体验式培训计划，使受训者掌握新的研究技能以及应用这些技能解决与疼痛和衰老有关的重要和悬而未决的问题的知识和专业知识；以及3)创建一种卓越的研究文化，以确保受训人员追求高标准的科学诚信和质量，这将为他们的未来奠定基调。 从事疼痛和衰老研究的职业。IMPAGE利用佛罗里达大学的两个优秀的协作研究项目--以老龄化研究所(IOA)为代表的老龄研究社区和由卓越疼痛研究和干预中心(PRICE)组织的疼痛研究社区。培训教师中的每一位成员都拥有出色的研究资金和指导经验。拟议的计划要求为四名来自不同培训背景的博士后实习生提供支持，每个人都将与他们的多学科指导团队合作，创建并实施一个量身定制的独立发展计划，作为他们培训的蓝图。学员将通过教学、研究和专业发展相结合的活动来实现他们的研究和职业发展目标，项目评估将是持续的和多模式的。传授计划致力于促进我们受训者的多样性，该计划将提供强调卓越研究诚信和道德的培训体验。

 DESCRIPTION (provided by applicant): As detailed in a recent Institute of Medicine (IOM) report, chronic pain represents a major public health concern, affecting 100 million U.S. adults and costing more than $500 billion annually. Aging confers increased risk for chronic pain, with half of older adults reporting persistent or recurring pain, and aging is associated with greater pain-related loss of physical and psychosocial function. Current knowledge regarding pain and aging is surprisingly limited, and future progress in the field hinges on the availability of well-trained scientists who have an appreciation for preclinical and clinical research approaches to the study of both aging and pain. At present, there are no existing NIH-funded T32 programs devoted to training in pain and aging. To address this unmet need, we propose to develop a new postdoctoral training program: the Integrative and Multidisciplinary Pain and Aging Research Training (IMPART) Program. The overall goal of the IMPART program is to develop outstanding independent investigators capable of sustaining productive clinical and translational research careers addressing the biopsychosocial mechanisms underlying age-related changes in the experience of pain and/or designing clinical interventions to ameliorate acute and chronic pain among older adults. In order to accomplish this overarching goal, the specific aims of this new postdoctoral training program in pain and aging research are to: 1) Recruit and train promising junior investigators to conduct mechanistically-based and clinically relevant translational research in pain and aging; 2) Implement an integrated didactic and experiential training program, which will equip trainees with new research skills and the knowledge and expertise to apply these skills to address important and unanswered questions regarding pain and aging; and 3) Create a culture of research excellence in order to ensure that trainees aspire to the high standards of scientific integrity and quality, which will set the tone for their future careers in pain and aging research. IMPART leverages two excellent and collaborative research programs at the University of Florida - the aging research community represented by the Institute on Aging (IOA), and the pain research community, organized under the Pain Research and Intervention Center of Excellence (PRICE). Each member of the training faculty boasts an excellent track record of both research funding and mentoring experience. The proposed program requests support for four postdoctoral trainees from a variety of training backgrounds, each of whom will work with their multidisciplinary mentoring team to create and implement a tailored independent development plan as the blueprint for their training. Trainees will achieve their research and career development objectives through a combination of didactic, research, and professional development activities, and program evaluation will be ongoing and multimodal. The IMPART Program is committed to promoting diversity among our trainees, and the program will provide a training experience that emphasizes excellence in research integrity and ethics.