Cancer Prevention and Control (CPC) (Project-004)

摘要-癌症预防和控制（CPC）研究 项目负责人：Paolo Boffetta，医学博士，公共卫生硕士和William Redd，博士 TCI癌症预防和控制（CPC）计划包括一系列丰富和互补的 癌症预防、控制和护理领域的研究项目。其总体目标是： 减少癌症发病率和死亡率的负担，以及（ii）改善受癌症影响的人的生活。 疾病CPC内的项目是沿着从初级预防到早期癌症的连续性发展的。 诊断、治疗和随访。CPC项目的特点是整合各部门的专业知识， 学科，包括临床科学，分子生物学和遗传学，流行病学，卫生服务研究， 健康心理学。 方案协调会的研究有两个贯穿各领域的主题。方案协调会内的许多项目处理以下方面的差异： 癌症风险和结果：在特殊人群中进行，如少数民族和 暴露于世贸中心袭击及其后果的个人，这可能会经历不成比例的负担， 癌此外，CPC的主要研究项目是基于多机构联盟的合作， 方案协调会成员在其中发挥关键的协调作用。CPC计划是 组织了沿着三个研究主题：（i）研究早期诊断和筛查的新方法 癌症和加强参与的方法，特别是少数群体的参与; ㈡分子癌症 流行病学研究，包括对特殊人群的研究，以及针对 与预防有关的致癌机制方面;（iii）旨在提高质量和 提供癌症护理，包括不同人群干预措施的比较有效性和成本 和设置，以了解和减少癌症的负面后遗症，通过个人，家庭和社区 参与战略。 CPC项目有25名成员，代表16个部门和3个研究所（蒂施癌症研究所 研究所，Arnhold全球健康研究所和糖尿病，肥胖和代谢研究所）。截至7月1日， 2014年，项目成员获得了NCI和其他同行评审的癌症相关直接资助6,587,718美元。 支持.中国共产党计划的成员在发表他们的研究成果方面越来越成功， 高影响力期刊自2011年以来，CPC计划成员发布了237份报告，其中16.9%是内部报告， 方案和5.5%方案间。

ABSTRACT – CANCER PREVENTION AND CONTROL (CPC) RESEARCH PROGRAM Program Leaders: Paolo Boffetta, MD, MPH and William Redd, PhD The TCI Cancer Prevention and Control (CPC) program encompasses a rich and complementary array of research projects in the areas of cancer prevention, control and care delivery. Its overarching goals are: (i) reducing the burden of cancer incidence and mortality, and (ii) improving the life of people affected by the disease. Projects within CPC are developed along the cancer continuum from primary prevention to early diagnosis, treatment and follow-up. CPC projects are characterized by the integration of expertise across disciplines, including clinical sciences, molecular biology and genetics, epidemiology, health services research, and health psychology. Two cross-cutting themes characterize research within CPC. Many projects within CPC address disparities in cancer risks and outcomes: they are conducted in special populations, such as ethnic minorities and individuals exposed to the WTC attack and its aftermath, which can experience a disproportionate burden of cancer. In addition, major CPC research projects are based on multi-institution consortia collaborations, both nationally and internationally, in which CPC members play a key coordinating role. The CPC program is organized along three Research Themes: (i) research on new methods on early diagnosis and screening of cancer and on approaches to enhance participation, in particular among minority groups; (ii) molecular cancer epidemiology research, including studies in special populations, and molecular-oriented studies addressing mechanistic aspects of carcinogenesis relevant to prevention; (iii) research aimed at improving the quality and delivery of cancer care, including comparative effectiveness and costs of interventions in diverse populations and settings, to understanding and reducing negative sequelae of cancer via individual, familial and community engagement strategies. The CPC program has 25 members, and they represent 16 departments and 3 institutes (The Tisch Cancer Institute, the Arnhold Global Health Institute, and the Diabetes, Obesity and Metabolism Institute). As of July 1, 2014, program members were awarded $6,587,718 in NCI and other peer-reviewed cancer-related direct support. Members of the CPC Program have been increasingly successful in publishing their research in high impact journals. Since 2011, CPC program members published 237 reports of which 16.9% were intra- programmatic and 5.5% inter-programmatic.