Cellular Approaches to Tissue Engineering and Regeneration

描述（由申请人提供）：匹兹堡大学寻求通过细胞方法组织工程和再生（CATER）培训计划为我们的再生医学多学科和创新的博士前培训提供持续支持。CATER计划结合了来自不同学科的教师和研究专业知识，这些学科将联合收割机组织工程与人类疾病和再生治疗的分子和细胞方法相结合。再生医学是一个真正的跨学科领域，汇集了来自人类生物学，工程，医疗器械，材料科学，医学和应用技术的科学家，专注于人体组织的修复和替换。再生医学最重大的挑战之一是在每个使能学科中培养下一代专家，这些专家必须接受培训，认识到再生医学成功实践所需的跨学科挑战和方法。为了解决这个问题，我们开发了CATER博士前培训计划，以填补更传统的以部门为中心的研究培训计划中经常存在的空白。CATER培训计划的目标是提供一个坚实的基础，在此基础上建立一个富有成效的和独立的职业生涯在人类疾病和损伤的再生医学。这一目标是通过一个高度协调和指导跨学科的培训计划，跨越部门和学科，并结合必修和选修课程，研究和专业培训机会。我们的历史（10年的资金支持）提供的证据表明，我们正在实现我们的培训目标，并产生成功的科学家。CATER计划成功的定义不断演变，过去的学员的职业选择概括了这一点，从本质上证明了他们的准备和需求，满足了学术界和工业界再生医学领域专家的及时需求。随着CATER计划进入第10个年头，我们现在意识到再生医学领域的成熟，各种各样的技术正在寻求商业化，以进入可报销临床护理领域。当我们提出未来五年的计划时，我们将继续建立我们的优势，同时接受当今再生医学不可或缺的及时概念和范式。我们在该计划中不断发展的课程反映了这些令人兴奋的时代，并通过与临床和转化科学研究所，库尔特计划和技术管理办公室的严格合作关系，体现了众所周知的板凳到床边，学术创业和转化医学的概念。因此，我们建议继续作为一个团队，通过CATER计划，通过协调，跨学科和严格的教学和研究培训，培养新一代从事再生医学的科学家。

DESCRIPTION (provided by applicant): The University of Pittsburgh seeks continued support for our multidisciplinary and innovative pre-doctoral training in Regenerative Medicine via Cellular Approaches to Tissue Engineering and Regeneration (CATER) training program. The CATER program combines faculty and research expertise from a diverse group of disciplines that combine tissue engineering with molecular and cellular approaches of therapies for human disease and regeneration. Regenerative medicine is truly an interdisciplinary field that brings together scientists from human biology, engineering, medical devices, material sciences, medicine and applied technologies to focus on the repair and replacement of human tissues. One of the most significant challenges in regenerative medicine is developing the next generation of experts in each of the enabling disciplines that must be trained cognizant of the cross-disciplinary challenges and approaches required for successful practice of regenerative medicine. To address this issue we developed the CATER pre-doctoral training program to fill the gaps that often exist in more traditional departmentally-focused research training programs. The goal of the CATER training program is to provide a solid foundation upon which to build a productive and independent career in regenerative medicine for human disease and injury. This goal is accomplished via a highly coordinated and mentored interdisciplinary training program that traverses departments and disciplines, and combines required and elective courses, research and specialized training opportunities. Our history (10-years of funding support) provides evidence that we are accomplishing our training objectives and generating successful scientists. The evolving definition of success for CATER program is recapitulated by the career choices of the past trainees that in essence demonstrates their preparedness and demand, fulfilling the timely need of experts in the area of regenerative medicine in both academics and industry. As CATER program moves into its 10th year, we now appreciate the maturation of the field of regenerative medicine such that a broad variety of technologies are seeking to be commercialized to cross into the area of reimbursable clinical care. As we propose the program for the next five years, we continue to build on our strengths and concurrently embrace the timely concepts and paradigms integral to regenerative medicine today. Our evolving curricula in the program reflects these exciting times and embodies the proverbial concepts of bench to bedside, academic entrepreneurship and translational medicine through rigorous partnerships with the Clinical and Translational Science Institute, the Coulter program and the Office of Technology Management. We thus propose to continue, as a team, train a new generation of scientists practicing regenerative medicine through coordinated, interdisciplinary and rigorous didactic and research training via the CATER program.