The Human Eukaryotic Translation Elongation Factor 1A is a Paramyxovirus Virus Dependency Factor
The Human Eukaryotic Translation Elongation Factor 1A is a Paramyxovirus Virus Dependency Factor
批准号:
nhmrc : 1065121
负责人:
A/Pr David Harrich
金额:
$39.04万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
几种副粘病毒在世界各地的婴儿、幼儿和老年人中引起呼吸道疾病。另一种可能由受感染的马感染的人感染的副粘病毒亨德拉病毒通常是致命的。目前还没有针对这些病毒的疫苗,治疗通常仅限于缓解症状。在这个项目中,我们将揭示这些病毒是如何利用人类蛋白质在细胞内生长的,目的是开发新的治疗策略。
英文摘要
Several paramyxoviruses cause respiratory disease in infants, young children and the elderly worldwide. Another paramyxovirus that can be contracted by people from infected horses, Hendra virus, is often fatal. There are currently no vaccines against these viruses, and treatment is generally limited to relief of symptoms. In this project we will uncover how these viruses use human proteins for their growth inside cells, with an aim to develop novel therapeutic strategies.
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海外基金