Preparative HPLC for the study of degradation products and metabolites

在全球水质和绿色能源的背景下，出现了新的研究领域。由拟议的基础设施支持的研究计划结合了两个相辅相成的研究领域：废水处理和定价。所需的分析设备是制备型高效液相色谱仪，可用于制备降解实验和生物制氢实验期间收集的样品，以进一步鉴定降解产物和代谢物。拟议的配置，包括一个紫外线探测器，还将允许在降解实验期间监测药物的浓度。研究的主要成果是技术和工艺的改进和发展，对从废水中生产生物氢的新见解，以及为高效和稳定地生产生物氢而开发的生物反应器和工艺。加拿大私营部门也将从这项研究中受益，通过组建高素质的人员和利用这项研究的机会来改进和开发减少药物在环境中的释放或允许使用具有成本效益的绿色工艺生产生物氢的技术。从长远来看，这项研究对环境和公众健康有明显的积极影响。

Within the global context of water quality and green energy new research areas have emerged. The research program that would be supported by the proposed infrastructure combined two complementary areas of research: treatment and valorization of wastewater. The analytical equipment requested, a preparative HPLC, will allow the preparation of samples collected during degradation experiment and biohydrogen production experiments for further identification of the degradation products and metabolites. The proposed configuration, including a UV detector, will also allow the monitoring of concentration of pharmaceuticals during the degradation experiments. The main outcomes of the research are the improvement and development of technologies and processes, new insight into the production of biohydrogen from wastewater and the development of bioreactors and processes for efficient and stable production of biohydrogen. The Canadian private sectors will also benefit from the research through the high qualified personnel formed and the opportunities to capitalize on this research to improve and develop technologies that mitigate the release of pharmaceuticals in the environment or allow the production of biohydrogen using cost-effective and green processes. On a longer term, the research has obvious positive impacts on environment and public health.