Research Fellowship
Research Fellowship
批准号:
nhmrc : 1022469
负责人:
A/Pr Jorg Heierhorst
金额:
$45.06万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
关键词:
中文摘要
DNA损伤反应通路在预防癌症的发生和调节化疗药物的临床反应中发挥重要作用,一些相关蛋白在正常发育过程中具有额外的功能。这项研究将研究一种新的人类蛋白质,它在肺的形成中起着关键作用,在防止DNA正常氧化损伤的破坏性后果中起着重要作用,以及在防止基因组突变中涉及的其他基本机制。
英文摘要
DNA damage response pathways play important roles in preventing the onset of cancer and regulating the clinical response to chemotherapeutics, and some of the relevant proteins have additional functions during normal development. This fellowship will study new a human protein with key roles in the formation of the lung, and its roles in preventing devastating consequences of normal oxidative damage to DNA, as well as additional fundamental mechanisms involved in preventing genome mutations.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
A tumour suppressor pathway that removes DNA-RNA hybrids
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批准号:nhmrc : GNT1139099
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项目类别:Project Grants
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资助金额:$93.58万
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财政年份:2018
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负责人:A/Pr Jorg Heierhorst
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依托单位:
A tumour suppressor pathway that removes DNA-RNA hybrids
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批准号:nhmrc : 1139099
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项目类别:Project Grants
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资助金额:$63.27万
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财政年份:2018
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Regulation and function of the Zinc-finger protein ASCIZ in the DNA damage response
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批准号:nhmrc : 1026125
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项目类别:Project Grants
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资助金额:$42.68万
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财政年份:2012
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Multi-domain regulation of DNA damage response kinases
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批准号:nhmrc : 1009764
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项目类别:NHMRC Project Grants
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资助金额:$20.9万
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财政年份:2011
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Developmental functions of a novel Zinc-finger protein
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批准号:nhmrc : 1009763
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项目类别:NHMRC Project Grants
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资助金额:$44.46万
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财政年份:2011
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Functions of ASCIZ in the repair of accidental and programmed DNA base damage
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批准号:nhmrc : 559020
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项目类别:NHMRC Project Grants
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资助金额:$40.88万
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财政年份:2009
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Identification of telomere-specific recombination pathways
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批准号:nhmrc : 502600
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项目类别:NHMRC Project Grants
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资助金额:$36.01万
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财政年份:2008
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Research Fellowship - Grant ID:448302
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批准号:nhmrc : 448302
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项目类别:NHMRC Research Fellowships
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资助金额:$37.31万
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财政年份:2007
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负责人:A/Pr Jorg Heierhorst
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依托单位:
DNA lesions involved in chemotherapy responses and their repair
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批准号:nhmrc : 395500
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项目类别:NHMRC Project Grants
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资助金额:$26.61万
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财政年份:2006
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Regulation and assembly of nuclear DNA repair centres
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批准号:nhmrc : 395501
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项目类别:NHMRC Project Grants
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资助金额:$30.49万
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财政年份:2006
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Functions of a novel conserved DNA damage response protein family in telomere stability
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批准号:nhmrc : 345419
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项目类别:NHMRC Project Grants
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资助金额:$18.86万
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财政年份:2005
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负责人:A/Pr Jorg Heierhorst
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依托单位:
FHA domain-dependent functions of cell cycle checkpoint kinases
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批准号:nhmrc : 247900
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项目类别:NHMRC Project Grants
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资助金额:$15.7万
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财政年份:2003
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 205305
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项目类别:NHMRC Research Fellowships
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资助金额:$33.64万
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财政年份:2002
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Function of the S100A1 Ca2+-binding protein under physiological and pathological conditions
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批准号:nhmrc : 156705
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项目类别:NHMRC Project Grants
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资助金额:$30.18万
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财政年份:2001
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Role of FHA domains as protein-protein interaction modules in cell signalling
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批准号:nhmrc : 124002
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项目类别:NHMRC Project Grants
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资助金额:$12.8万
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财政年份:2000
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Physiological function of the calcium binding protein S100A12
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批准号:nhmrc : 981176
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项目类别:NHMRC Project Grants
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资助金额:$13.11万
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财政年份:1998
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负责人:A/Pr Jorg Heierhorst
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依托单位:
Molecular mechanisms of signalling by S100 CA2+ -binding proteins
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批准号:nhmrc : 987720
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项目类别:Career Development Fellowships
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资助金额:$17.57万
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财政年份:1998
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负责人:A/Pr Jorg Heierhorst
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依托单位:
海外基金