Structure and dynamics of aerosols and nanoparticles

人们对分子纳米粒子、气溶胶和直径从亚纳米到微米的团簇的兴趣迅速增长，这是因为它们在许多不同领域的相关性越来越大。组成变化很大的分子粒子被认为起着重要的作用，例如在大气过程中充当气溶胶或在星际尘埃中充当活性位点。在这种情况下，了解这些粒子的化学成分、大小和反应性以及它们形成的过程显然是至关重要的。控制它们形成的能力不仅是实验室研究的先决条件，而且还开辟了其他应用领域，如药物制剂的纳米颗粒。这里的主要目标是制备封装或包被的药物颗粒，用于在医疗应用中控制甚至靶向药物输送。

The rapidly growing interest in molecular nanoparticles, aerosols, and clusters with diameters ranging from subnanometers to microns arises from their increasing relevance in many different fields. Molecular particles of widely varying composition are seen to play an important role, e. g. as aerosols in atmospheric processes or as reactive sites in interstellar dust. In this context it is obviously crucial to know the chemical composition, the size, and the reactivity of these particles and to understand the processes by which they are formed. The ability to control their formation is not only a prerequisite for laboratory studies, but also opens up other fields of application such as nanoparticles of pharmaceutical agents. The major goal here is the preparation of encapsulated or coated drug particles for controlled or even targeted drug delivery in medical applications.