Theoretical models of the evolutionary genetics of adaptation

进化生物学和生态学的一个主要目标是确定生物多样性的决定因素。自孟德尔以来，基因遗传已被确定为生物多样性的基本决定因素；遗传为达尔文的遗传修正原理提供了物理基础。基因遗传是一个系谱过程，即一代人的基因是过去几代人的基因的后代。最近，我和我的同事们发现，谱系过程在一定程度上决定了一个种群的形态变异方向。先前形态学变异的遗传基础模型忽略了谱系，他们关注突变、等位基因频率和选择。

A major goal of evolutionary biology and ecology is to identify the determinants of biodiversity. Since Mendel, genetic inheritance has been identified as a fundamental determinant of biodiversity; inheritance provides the physical basis for Darwin's principle of descent with modification. Genetic inheritance is a genealogical process, whereby genes present in one generation are descents of genes that were present in past generations. Recently my colleagues and I discovered that the genealogical process determines, in part, the directions of morphological variation in a population. Previous models of the genetic basis of morphological variation overlooked genealogy, they had focused on mutation, allele frequencies and selection.