Unravelling the genetics of the common epilepsies using discordant monozygotic twins

癫痫是澳大利亚人群中的常见疾病，影响3%的个体，具有显著的遗传贡献。为了改善病人的护理，我们将研究一组独特的同卵双胞胎不一致的不同类型的常见遗传性癫痫。鉴定与常见癫痫有关的新基因将为患者及其家属提供与预后、复发风险和治疗选择相关的信息。它将加强澳大利亚在癫痫方面长期建立的临床和研究专业知识。

Epilepsy is a common disease in the Australian population affecting 3% of individuals that has a significant genetic contribution. To improve patient care we will study a unique set of identical twins discordant for different types of common genetic epilepsies. Identification of novel genes involved in common epilepsies will provide information relevant to prognosis, recurrence risks and treatment options for patients and their families. It will enhance long established Australian clinical and research expertise in epilepsy.