Theoretical models of the evolutionary genetics of adaptation

进化生物学和生态学的一个主要目标是确定生物多样性的决定因素。 自孟德尔以来，遗传被认为是生物多样性的一个基本决定因素;遗传为达尔文的遗传变异原则提供了物质基础。 基因遗传是一个系谱学过程，其中存在于一代人中的基因是存在于过去几代人中的基因的后代。 最近，我和我的同事们发现，系谱学过程在一定程度上决定了种群中形态变异的方向。 以前的形态变异的遗传基础模型忽略了系谱学，他们专注于突变，等位基因频率和选择。

A major goal of evolutionary biology and ecology is to identify the determinants of biodiversity. Since Mendel, genetic inheritance has been identified as a fundamental determinant of biodiversity; inheritance provides the physical basis for Darwin's principle of descent with modification. Genetic inheritance is a genealogical process, whereby genes present in one generation are descents of genes that were present in past generations. Recently my colleagues and I discovered that the genealogical process determines, in part, the directions of morphological variation in a population. Previous models of the genetic basis of morphological variation overlooked genealogy, they had focused on mutation, allele frequencies and selection.