Bio-based approaches for the prevention and treatment of fungus (Saprolegnia parasitica) in fish.

据联合国粮食及农业组织称，人们日益认识到疾病爆发是对水产养殖生产和贸易的重大制约，并正在影响世界许多国家该部门的经济发展。真菌病是水产养殖，特别是贝类和鱼类养殖中第二大死亡原因。其中最具破坏性的病原体之一，对淡水水产养殖部门的经济影响最大的是寄生菌。有证据表明在大多数淡水鱼中广泛感染；如果不及时治疗，腐殖质增生可迅速升级，导致特定人群高达50%的死亡率。对用于预防和治疗真菌感染的化学品使用的新限制导致需要新的替代产品来控制坏疽。目前的建议寻求应用新的方法来治疗和预防真菌感染，利用从北方森林生物量中提取的有益微生物培养物和/或植物化学物质。鉴定可用于治疗和/或预防病原体传播的新型天然化合物将为水产养殖生产者提供预防和控制疾病的额外管理方法，并使该行业能够采用无害环境的技术，为加拿大消费者生产安全、健康的产品。

According to the United Nation's Food and Agriculture Organization, disease outbreaks are being increasingly recognized as a significant constraint to aquaculture production and trade, and are affecting economic development of the sector in many countries of the world. Fungal diseases are the second largest cause of mortality in aquaculture, particularly in the cultivation of shellfish and fish species. One of most destructive pathogens and that having the greatest economic impact in freshwater aquaculture sectors is the fungus Saprolegnia parasitica. Evidence suggests widespread infection in most freshwater fish species; left untreated, saprolegniosis can quickly escalate, resulting in up to 50% mortalities of a given population. New restrictions on the use of chemicals used to prevent and treat fungal infections has lead to the need for new alternative products to control saprolegniosis. The current proposal seeks to apply novel approaches to treat and prevent fungal infections using beneficial microbial cultures and or phytochemicals derived from boreal forest biomass. The identification of novel natural compounds that can be used to treat and/or prevent the transmission of pathogens would provide aquaculture producers additional management approaches for disease prevention and control, and permit the industry to pusue environmentally-sound technologies to permit production ofsafe, healthy products for Canadian consumers.