Time-of-flight mass spectrometry of biomolecules using particle and laser induced desorption
Time-of-flight mass spectrometry of biomolecules using particle and laser induced desorption
批准号:
38415-2011
负责人:
Ens, Werner
金额:
$1.6万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2014-12-31
中文摘要
基因技术的巨大发展,以及包括人类在内的多种生物基因组序列的完成,为快速、灵敏地测定蛋白质的特性和功能提供了前所未有的机会。在蛋白质组学的这一领域,质谱法起着关键的作用,由于在这一领域同样戏剧性的发展,其中许多是在物理实验室。80年代末,两种新的电离技术——基质辅助激光解吸/电离(MALDI)和电喷雾电离(ESI)的发明,在很大程度上克服了可获得的质量范围和灵敏度的限制。2002年诺贝尔化学奖的部分原因就是这些进展。
英文摘要
The dramatic developments in gene technology, and the completion of genome sequences for a variety of organisms, including humans, provide unprecedented opportunities for rapid and sensitive determination of the identity and function of proteins. In this field of proteomics, mass spectrometry plays a pivotal role, due to similarly dramatic developments in this field, many of them in physics laboratories. In the late 80s, limited accessible mass range and sensitivity were largely overcome by the invention of two new ionization techniques, matrix-assisted laser desorption/ionization (MALDI), and electrospray ionization (ESI). The 2002 Nobel prize in Chemistry was awarded in part for these developments.
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Time-of-flight mass spectrometry of biomolecules using particle and laser induced desorption
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批准号:38415-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.6万
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财政年份:2015
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particle and laser induced desorption
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批准号:38415-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.6万
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财政年份:2014
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particle and laser induced desorption
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批准号:38415-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.6万
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财政年份:2012
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particle and laser induced desorption
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批准号:38415-2011
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.6万
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财政年份:2011
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particel and laser induced desorption
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批准号:38415-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.8万
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财政年份:2010
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particel and laser induced desorption
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批准号:38415-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.8万
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财政年份:2009
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particel and laser induced desorption
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批准号:38415-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.8万
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财政年份:2008
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particel and laser induced desorption
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批准号:38415-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.8万
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财政年份:2007
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负责人:Ens, Werner
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依托单位:
Time-of-flight mass spectrometry of biomolecules using particel and laser induced desorption
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批准号:38415-2006
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.8万
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财政年份:2006
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules
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批准号:38415-2001
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
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财政年份:2004
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules
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批准号:38415-2001
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
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财政年份:2003
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules
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批准号:38415-2001
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
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财政年份:2002
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules
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批准号:38415-2001
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.38万
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财政年份:2001
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules and clusters
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批准号:38415-1997
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.26万
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财政年份:2000
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules and clusters
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批准号:38415-1997
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.26万
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财政年份:1999
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules and clusters
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批准号:38415-1997
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.2万
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财政年份:1998
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules and clusters
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批准号:38415-1997
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.09万
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财政年份:1997
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负责人:Ens, Werner
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依托单位:
Fundamental processes in desorption time-of flight mass spectrometry of large molecules and clusters
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批准号:38415-1995
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.21万
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财政年份:1995
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负责人:Ens, Werner
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依托单位:
Particle and laser induced desorption of clusters and large molecules
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批准号:38415-1992
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.17万
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财政年份:1994
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负责人:Ens, Werner
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依托单位:
Particle and laser induced desorption of clusters and large molecules
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批准号:38415-1992
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.17万
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财政年份:1993
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负责人:Ens, Werner
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依托单位:
国内基金
海外基金
Time-of-Flight深度相机多径干扰问题的研究
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批准号:61901435
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项目类别:青年科学基金项目
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资助金额:25.0万元
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批准年份:2019
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负责人:张越一
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依托单位:
四足机器人Flight Trot步态切换控制方法研究
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批准号:61903131
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项目类别:青年科学基金项目
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资助金额:25.0万元
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批准年份:2019
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负责人:郞琳
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依托单位:
基于飞行时间技术的新一代正电子发射断层扫描技术研究
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批准号:10775149
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项目类别:面上项目
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资助金额:40.0万元
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批准年份:2007
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负责人:魏龙
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依托单位: