Interpenetrating network of a well-defined PEG hydrogel and two biocides as advanced solutions for burn wound care

烧伤是一种由火、热、电、化学物质、辐射或摩擦引起的皮肤损伤。它发生在所有年龄段。烧伤创面感染仍然是皮肤移植失败的主要原因，也是烧伤相关死亡的主要原因之一。浸渍银化合物的敷料是治疗烧伤创面的主要方法。然而，许多市面上可买到的银基伤口敷料在移除时会因粘连伤口床而造成创伤。最近的一项研究表明，烧伤敷料相关的疼痛与更严重的抑郁和创伤后应激症状有关。此外，与银基伤口敷料相关的新出现的抵抗力是一个日益令人担忧的问题。

A burn is a type of injury to the skin caused by fire, heat, electricity, chemicals, radiation or friction. It occurs in all age groups. Burn wound infection remains the leading cause of skin graft failure and one of the leading causes of burn injury related mortality. Dressings impregnated with silver compounds are the mainstay of treatment for burn wounds. However, many commercially available silver based wound dressings cause trauma upon removal because of adhesion to the wound bed. A recent study has shown that burn dressing related pain is related to more severe depressive and posttraumatic stress symptoms. Furthermore, emerging resistance associated with silver based wound dressings is a growing concern.