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Metabolic manipulation of hypoxia and radiotherapy response

Metabolic manipulation of hypoxia and radiotherapy response
缺氧和放疗反应的代谢调控
批准号:
293382
负责人:
Minchinton Andrew I
金额:
$52.97万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-09-01 至 2018-09-01

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项目成果

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中文摘要
翻译
随着癌症的生长,它们经常会超过血液供应,从而导致肿瘤中的缺氧区域,在那里细胞处于低氧张力状态。肿瘤内的低氧状态长期以来被认为对肿瘤的侵袭性和辐射有深远的影响
英文摘要
As cancers grow they often outstrip their blood supply which leads to hypoxic regions in tumours, where cells exist at low oxygen tension. Low oxygen status within tumours has long been known to have a profound effect on tumour aggressiveness and radiati
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会议论文
Development of clinical candidate hypoxia-activated DNA-PK inhibitors
FLASH radiotherapy - mechanisms and translational studies
Metabolic manipulation of hypoxia for improved radiotherapy response
Hypoxia-activated DNA repair inhibitors to improve cancer therapy
国内基金
海外基金
一碳代谢(One carbon metabolism)介导上调的 PD1/PDL1 驱动 肿瘤免疫逃逸
  • 批准号:
    2024JJ9491
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    彭罗根
  • 依托单位: