CMOS based 500 MHz NMR probe technology

核磁共振可以说是研究化学结构、动力学和相互作用的最强大的工具，其应用范围涵盖化学、生物化学、材料科学和医学。然而，传统的核磁共振系统一次只能分析一个样品。在这个合作项目中，核磁共振波谱仪器的市场领先者布鲁克有限公司和约克大学拉松德工程学院的生物灵感传感器和执行器实验室提出了一种新颖的电子活性核磁共振探测器技术。这种核心集成的微流控互补金属氧化物半导体(ImCMOS)技术是迈向高通量筛选平台的关键第一步，适用于各种生命科学应用，包括小型生物、细胞和组织的毒性研究。该项目的成功，不仅增进了我们对这项技术的了解，也提高了加拿大大学的科研质量。

Nuclear Magnetic Resonance (NMR) is arguably the most powerful tool for the study of chemical structure, dynamics and interactions with a range of applications spanning chemistry, biochemistry, material science and medicine. However, conventional NMR systems are limited to the analysis of one sample at a time. In this collaborative project, Bruker Ltd. - the market leader in NMR spectroscopy instruments and the Biologically Inspired Sensors and Actuators Laboratory at the Lassonde School of Engineering, York University propose a novel electronically active NMR probe technology. This core- integrated Microfluidic Complementary Metal Oxide semiconductor (imCMOS) technology is the key first step towards a high throughput screening platform for various life science applications including toxicity studies of small organisms, cells and tissues. The success of this project, not only enhance our knowledge in this technology but also improve the quality of scientific research in Canadian Universities.