Exploiting XtalFluor reagents in organic synthesis and developing new approaches to pentafluorosulfanyl-containing molecules

本文所述的项目旨在开发用于制备有机化合物的新合成工具，特别是在制药工业、农业化学以及材料科学中具有高度兴趣的含氟分子。具体目标是：1）使用OmegaChem的XtalFluor试剂改进脱氧反应; 2）发现使用OmegaChem的XtalFluor试剂合成氟化（磺酰氟）和非氟化化合物（酰基卤）的新转化; 3）开发含五氟硫烷基化合物的新合成方法。总的来说，这些项目在OmegaChem不断努力向市场推出新分子的背景下具有重要意义，这些新分子可以整合到更复杂的结构设计中，展示出创新的特性和更高的效率。

The projects described herein aim at the development of new synthetic tools for the preparation of organic compounds, in particular fluorine-containing molecules which are of high interest in pharmaceutical industry, in agrochemistry as well as in material sciences. Specific objectives are: 1) the improvement of the deoxofluorination reaction using OmegaChem's XtalFluor reagents; 2) the discovery of new transformations using OmegaChem's XtalFluor reagents for the synthesis of fluorinated (sulfonyl fluorides) and non-fluorinated compounds (acyl halides); and 3) the development of novel synthetic approaches to pentafluorosulfanyl-containing compounds. Overall, these projects are significant in the context that OmegaChem is continually working to introduce on the market new molecules that can be integrated to the design of more complex structures demonstrating innovative properties and increased efficiency.