Engineering Research Equipment Grant: Liquid Scintillation Counter

这项研究工作的目的是了解基本的新陈代谢， 微生物和哺乳动物细胞，并利用这些信息来改变 反应体系的生产率。 液体闪烁计数器 将用于以下项目：（1）生物聚合物的影响 微粒对细菌生物膜代谢和生态的影响;（2） 通过底物提高多形汉逊酵母中的酶生产率 组成和生长速率瞬变;（3）粘附对 微生物的代谢， 复合物在地下水中的降解;（4）热化学控制 次级代谢产物的质量、产量和生产率-合成 野油菜黄单胞菌多糖黄原胶;和（5） 单克隆抗体的动力学和优化工程研究 通过杂交瘤生产。

This research effort is aimed at understanding the basic metabolism of microbial and mammalian cells and to use that information to alter the productivity of the reaction system. A liquid scintillation counter will be used for the following projects: (1) effects of biopolymer particulates on the metabolism and ecology of bacterial biofilms; (2) enhanced enzyme productivity in Hansenula polymorpha by substrate composition and growth rate transients; (3) influence of adhesion on the metabolism of microbes genetically-engineered for xenobiotic compound degradation in the ground water; (4) thermochemical control of secondary metabolite quality, yield, and production rate-synthesis of the polysaccharide Xanthan by Xanthamonas campestris; and (5) engineering studies of kinetics and optimization of monoclonal antibody production by a hybridoma.