U.S.-Hungary Biophysics Research on Low Energy Conformation of Polypeptides

美国这次行动的主要目标是：S.-匈牙利合作研究 康奈尔大学的哈罗德·舍拉加博士和 匈牙利科学院酶学研究所的Istvan Simon博士 是从事蛋白质折叠的理论研究。 一个有希望的统计方法，其特点是“积累”，将 可用于联合收割机的构象能计算， 氨基酸序列的统计分析， 蛋白质的三维结构。 结果可能会产生 合理、有效的方法来确定构象 低能量肽 这个生物物理学项目实现了以下计划目标： 促进科学知识，使美国的专家 国家和东欧联合收割机互补人才和汇集 在共同感兴趣和能力强的领域的研究资源。

The primary objective of this U. S.- Hungary cooperative research project between Dr. Harold Scheraga of Cornell University and Dr. Istvan Simon of the Institute of Enzymology, Hungarian Academy of Sciences, is to pursue theoretical studies of protein folding. A promising statistical approach, characterized as "build-up," will be employed to combine conformational energy calculations on oligopeptides with statistical analyses of amino acid sequences and of three dimensional protein structures. Results may yield a rational, effective approach for determining the conformation of low-energy peptides. This project in biophysics fulfills the program objective of advancing scientific knowledge by enabling experts in the United States and Eastern Europe to combine complementary talents and pool research resources in areas of strong mutual interest and competence.