Genetic Recombination and Genome Rearrangements Copper Mountain, Colorado, July 1989

这笔赠款支持1989年7月9日至14日在科罗拉多州铜山举行的FASEB关于遗传重组和基因组重排的夏季研究会议。这次会议是由美国实验生物学学会联合会(FASE B)主办的。这次会议的形式将与戈登研究会议使用的相同。将有九个主要会议，36位受邀演讲者。每届会议主席将作介绍性演讲，介绍会议的历史背景和当前存在的问题，以使所有与会者了解会议的主题。招贴会将在整个会议期间举行。在会议之前或会议期间将安排小组的非正式讲习班。这次会议是美国唯一一次专门讨论基因重组和基因组重组的定期会议。本次会议将讨论的议题包括：当前的基因治疗方法，导致癌症的基因组重排，同源重组的遗传学，同源重组的酶学(链转移酶、核酸酶和分解酶)，重组中间体的物理结构，异源双链重组中间体错配位点的修复，位点特异性重组和基因表达的调控，细菌和真核生物的转座。

This grant supports a FASEB Summer Research Conference on Genetic Recombination and Genome Rearrangements, held July 9-14, 1989 in Copper Mountain, Colorado. The conference is under the auspices of the Federation of the American Societies of Experimental Biology (FASEB). The format of this meeting will be the same as that used by the Gordon Research Conferences. There will be nine major sessions with 36 invited speakers. The chairperson of each session will give an introductory talk on the historical background and the current problems to acquaint all participants with the topics in that session. Poster sessions will be held throughout the meeting. Informal workshops of small groups will be arranged before or at the meeting. This conference is the only regularly scheduled meeting in the United States that is devoted exclusively to genetic recombination and genome rearrangements. The topics to be covered at this meeting are current approaches to gene therapy, genome rearrangements that lead to cancer, genetics of homologous recombination, enzymology of homologous recombination (strand transferases, nucleases, and resolvases), physical structure of recombination intermediates, repair of mismatch sites in heteroduplex recombination intermediates, site-specific recombination and regulation of gene expression, and bacterial and eukaryotic transposition.