New Modes of Metallacycle and Carbene Reactivity

在这个由无机、生物无机和有机金属化学项目支持的项目中，加州大学圣地亚哥分校的Joseph M. O'Connor将继续在金属循环和碳化学界面的有机金属研究领域进行研究。这项研究直接影响了金属碳在烯烃复分解、烯烃和炔的聚合、环丙烷化学和一系列令人印象深刻的合成有机方法中的作用。提出的研究重点是铱、铑和钴化合物，以及发展新的碳偶联反应，其中上述金属的环扩展金属环和最终的四元和五元碳环将是可获得的。除了综合研究外，还将进行结构和机械研究。

In this project supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program, Joseph M. O'Connor of the University of California, San Diego will continue studies in the area of organometallic research at the interface of metallacycle and carbene chemistry. This research directly impinges on the role of metal carbenes in alkene metathesis, alkene and alkyne polymerization, cyclopropanation chemistry and an impressive array of synthetic organic methodology. The proposed research has its focus on iridium, rhodium and cobalt compounds and the development of new carbene coupling reactions wherein ring-expanded metallacycles of the above metals and ultimately four- and five-membered carbocycles would be accessible. In addition to the synthetic studies, structural and mechanistic studies will also be carried out.