New Modes of Metallacycle and Carbene Reactivity

在这个由无机，生物无机和 有机化学程序，约瑟夫M。奥康纳 加州大学圣地亚哥分校将继续在 界面有机金属研究领域 金属乳糖和卡宾化学。这项研究直接 影响了金属卡宾在烯烃复分解中的作用， 烯烃和炔烃聚合，环丙烷化化学 以及一系列令人印象深刻的有机合成方法 拟议的研究重点是铱，铑和 钴化合物与新型卡宾偶联反应的研究进展 反应，其中上述的扩环金属杂环 金属和最终的四元和五元碳环将 变得平易近人除了合成研究外， 并进行机理研究。

In this project supported by the Inorganic, Bioinorganic and Organometallic Chemistry Program, Joseph M. O'Connor of the University of California, San Diego will continue studies in the area of organometallic research at the interface of metallacycle and carbene chemistry. This research directly impinges on the role of metal carbenes in alkene metathesis, alkene and alkyne polymerization, cyclopropanation chemistry and an impressive array of synthetic organic methodology. The proposed research has its focus on iridium, rhodium and cobalt compounds and the development of new carbene coupling reactions wherein ring-expanded metallacycles of the above metals and ultimately four- and five-membered carbocycles would be accessible. In addition to the synthetic studies, structural and mechanistic studies will also be carried out.