New Modes of Metallacycle and Carbene Reactivity

在这个由无机，生物无机， 有机化学程序，约瑟夫M。奥康纳 内华达州大学里诺分校将继续在该地区进行研究 金属有机化合物研究在金属镧系元素和 卡宾化学 研究的目标是开发 产生扩环的新的卡宾偶联反应 铱、铑或钴的金属杂环， 四元和五元碳环。 游离卡宾-卡宾 也可以生成产品。 除了合成的 工作，结构和机械研究将在 为了阐明协调几何的作用，辅助 配体和环取代基对插入过程的影响。 %%% 这一研究直接影响到金属卡宾的作用 在烯烃复分解、烯烃和炔烃聚合中， 环丙烷化化学和令人印象深刻的合成 有机方法论。

In this project supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program, Joseph M. O'Connor of the University of Nevada at Reno will continue studies in the area of organometallic research at the interface of metallacycle and carbene chemistry. The goal of the research is development of new carbene coupling reactions which produce ring-expanded metallacycles of iridum, rhodium, or cobalt and ultimately four- and five-membered carbocycles. Free carbene-carbene products may also be generated. In addition to the synthetic work, structural and mechanistic studies will be carried out in order to clarify the effect of coordination geometry, ancillary ligands, and ring substituents on the insertion process. %%% This research directly impinges on the role of metal carbenes in alkene metathesis, alkene and alkyne polymerization, cyclopropanation chemistry and an impressive array of synthetic organic methodology.