New Modes of Metallacycle and Carbene Reactivity

在这个由无机、生物无机和有机金属化学项目支持的项目中，内华达大学里诺分校的约瑟夫·m·奥康纳（Joseph M. O'Connor）将继续在金属循环和二氧化碳化学界面的有机金属研究领域进行研究。这项研究的目标是开发新的碳偶联反应，这种反应可以产生铱、铑或钴的金属环，最终产生四元和五元碳环。游离碳-碳产物也可能生成。除了合成工作外，还将进行结构和机理研究，以阐明配位几何、辅助配体和环取代基对插入过程的影响。这项研究直接影响了金属碳在烯烃复分解、烯烃和炔的聚合、环丙烷化学和一系列令人印象深刻的合成有机方法中的作用。

In this project supported by the Inorganic, Bioinorganic, and Organometallic Chemistry Program, Joseph M. O'Connor of the University of Nevada at Reno will continue studies in the area of organometallic research at the interface of metallacycle and carbene chemistry. The goal of the research is development of new carbene coupling reactions which produce ring-expanded metallacycles of iridum, rhodium, or cobalt and ultimately four- and five-membered carbocycles. Free carbene-carbene products may also be generated. In addition to the synthetic work, structural and mechanistic studies will be carried out in order to clarify the effect of coordination geometry, ancillary ligands, and ring substituents on the insertion process. %%% This research directly impinges on the role of metal carbenes in alkene metathesis, alkene and alkyne polymerization, cyclopropanation chemistry and an impressive array of synthetic organic methodology.