Homogeneous Catalytic Carbonylation of Nitroaromatics and Related Studies

硝基芳烃的均相催化羰基化反应及相关研究

• 批准号: 9021923
• 负责人: Wayne Gladfelter
• 金额: $ 15.88万
• 依托单位: University of Minnesota-Twin Cities
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-02-15 至 1993-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9021923&HistoricalAwards=false
• 关键词: Homogeneous; Catalytic; Carbonylation; Nitroaromatics; Related

In this project in the Inorganic, Bioinorganic, and Organometallic Program of the Chemistry Division, Gladfelter will study how certain catalysts promote the conversion of nitroaromatic compounds into isocyanates. A possible outcome of the project is a safer and more environmentally benign method for the production of isocyanates, an important class of commercial chemicals. Attempts will be made to elucidate the mechanism of the homogeneous catalytic carbonylation of nitroaromatics, a reaction that may be capable of replacing the current phosgene- based technology for the production of isocyanates. The methods involve kinetic studies of the catalysis, in situ FTIR and NMR spectroscopies conducted at high temperature and pressure, and isolation and characterization of catalytic intermediates. Three ruthenium carbonyl catalysts will be studied: a monomer containing the bis(diphenylphosphino)methane ligand, the recently discovered binuclear species containing two bis(dimethylphosphino)methane ligands, and triruthenium dodecacarbonyl.

在化学部无机、生物无机和有机金属项目的这个项目中，Gladfelter将研究某些催化剂如何促进硝基芳香族化合物转化为异氰酸酯。该项目的一个可能结果是一种更安全、更环保的生产异氰酸酯的方法，异氰酸酯是一类重要的商业化学品。将尝试阐明硝基芳烃均相催化羰基化反应的机理，该反应可能能够取代目前基于光气的异氰酸酯生产技术。这些方法包括催化动力学研究，在高温高压下进行的原位FTIR和NMR光谱，以及催化中间体的分离和表征。三种钌羰基催化剂将被研究：一种含有二（二苯基膦）甲烷配体的单体，最近发现的含有两个二（二甲基膦）甲烷配体的双核物种和三钌十二羰基。