Gordon Conference on Fibronectin and Related Macromolecules in Oxnard, CA (February 15-20, 1993)

要求为将于1993年2月在加利福尼亚奥克斯纳德举行的关于纤维连接蛋白和有关大分子的戈登会议提供资金。细胞外黏附素，纤维连接蛋白，与跨膜受体相互作用的范例已被证明适用于许多黏附系统。同时也认识到，纤维连接蛋白的跨膜受体只是功能和结构相关的细胞表面受体整合素家族的一个成员。这些受体及其配体参与了包括植物在内的所有类型细胞的许多基本功能，如粘附、形状决定、分化、迁移、细胞骨架组织和细胞外基质的组织。未来几年，该领域面临的挑战是理解和组织大量新的结构信息，并在此基础上进行设计实验。这次会议将作为一个有价值的论坛来展示和讨论新的信息，确定问题领域，并计划新的方法。

Funds are requested for a Gordon Conference on fibronectin and related macromolecules to meet in Oxnard, California, in February 1993. The paradigm of an extracellular adhesin, fibronectin, interacting with a transmembrane receptor has proven applicable to a number of adhesion systems. In parallel has come the realization that the transmembrane receptor for fibronectin is only one member of the integrin family of functionally and structurally related cell surface receptors. These receptors and their ligands are involved in many basic functions of cells of all types, including plants, e.g., adhesion, determination of shape, differentiation, migration, cytoskeletal organization, and organization of extracellular matrix. The challenge to the field over the next several years is to comprehend and organize the large amount of new structural information and design experiments based on it. This conference will serve as a valuable forum to present and discuss new information, identify problem areas, and plan new approaches.