Gordon Conference on Fibronectin, Integrins, and Related Macromolecules, to be held February 1995 at Oxnard, California

戈登纤维连接蛋白、整合素和相关大分子会议，将于 1995 年 2 月在加利福尼亚州奥克斯纳德举行

• 批准号: 9413029
• 负责人: Carlyle Storm
• 金额: $ 0.35万
• 依托单位: Gordon Research Conferences
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1995
• 资助国家: 美国
• 起止时间: 1995-01-01 至 1995-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9413029&HistoricalAwards=false
• 关键词: Gordon; Conference; Fibronectin; Integrins; Related

9413029 Storm The Gordon Research Conference on "Fibronectin, Integrins, and Related Macromolecules" will be held in February, 1995 in Oxnard, California. As the paradigm of an extracellular adhesin, fibronectin interactions with a transmembrane receptor have proven applicable to a number of cellular adhesion systems. Many other extracellular glycoproteins have been described with biological properties similar to fibronectin, most of which have been sequenced and some of which have known three dimensional structures. These molecules are involved in a wide variety of basic cellular functions in metazoans, of significance to such areas of study as embryogenesis, tissue organization, hemostasis, wound healing, immune functions, and pathological states. Proteins of this type have also been discovered in higher plants, and their functions in plants remains to be understood. The challenges to the field over the next several years are to comprehend and organize the large amount of new structural information and design experiments based on it, learn the relative biological importance of the several seemingly redundant adhesion systems in animal tissues, and apply the new insights to practical ends. The 1995 Gordon Research Conference will serve as a valuable forum to present and discuss new information, identify problem areas, and plan new approaches. This grant provides partial support for expenses of conferees with limited travel funds who would otherwise not be able to attend, as well as applicants whose research involves plants. ***

小行星9413029 关于“纤维连接蛋白、整合素和相关大分子”的戈登研究会议将于1995年2月在加州的奥克斯纳德举行。 作为细胞外粘附素的范例，纤连蛋白与跨膜受体的相互作用已被证明适用于许多细胞粘附系统。 许多其他胞外糖蛋白已被描述为具有与纤连蛋白相似的生物学特性，其中大部分已被测序，并且其中一些具有已知的三维结构。 这些分子参与后生动物的多种基本细胞功能，对胚胎发生、组织组织形成、止血、伤口愈合、免疫功能和病理状态等研究领域具有重要意义。 这种类型的蛋白质也已在高等植物中发现，它们在植物中的功能仍有待了解。 未来几年该领域面临的挑战是理解和组织大量新的结构信息，并基于此设计实验，了解动物组织中几个看似冗余的粘附系统的相对生物学重要性，并将新的见解应用于实际目的。 1995年戈登研究会议将作为一个宝贵的论坛，提出和讨论新的信息，确定问题领域，并计划新的方法。这项补助金为旅费有限而无法参加会议的与会者以及研究涉及植物的申请人提供部分支助。 ***