New Carbon-Carbon Bond-Forming and -Cleaving Organometallic Reactions

新的碳-碳键形成和断裂有机金属反应

• 批准号: 9402288
• 负责人: Ei-ichi Negishi
• 金额: $ 38.4万
• 依托单位: Purdue Research Foundation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-05-15 至 1997-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9402288&HistoricalAwards=false
• 关键词: New; Carbon; Bond; Forming; Cleaving

9402288 Negishi The focus of this research is the development of carbon-carbon bond making and bond breaking processes that use zirconium mediated methodology. Bis(cyclopentadienyl)zirconium derivatives are used to probe a wide range of organometallic reactions that involve catalysis and have the potential for enantioselectivity. %%% With this renewal award, the Synthetic Organic Program is supporting the research of Dr. Ei-Ichi Negishi of the Department of Chemistry at Purdue University. Professor Negishi will focus his efforts on developing new catalytic methods for the formation and breaking of carbon-carbon bonds. Organometallic reactions featuring zirconium reagents are the key to the strategy. ***

9402288 Negishi 这项研究的重点是开发使用锆介导方法的碳-碳键形成和键断裂过程。 双（环戊二烯基）锆衍生物可用于探测涉及催化并具有对映选择性潜力的各种有机金属反应。 %%% 凭借这一续签奖项，合成有机项目正在支持普渡大学化学系 Ei-Ichi Negishi 博士的研究。 根岸教授将致力于开发碳-碳键形成和断裂的新催化方法。 以锆试剂为特色的有机金属反应是该策略的关键。 ***