Acquisition of a Laser Desorption Time-of-Flight Mass Spectrometer

这份来自学术研究基础设施项目的合同将帮助迈阿密大学化学系获得一台用于研究的激光解吸飞行时间质谱仪。将得到支持的研究活动包括两个一般部分：发展方法以扩展激光解吸飞行时间质谱法的能力，并将该技术应用于正在进行的研究问题。与技术发展有关的项目包括对基质辅助机制的调查和对二次离子生产的研究。建议的应用涉及分子生物学，材料科学，电化学和生物分析化学。质谱（MS）是一种用于探测内部结构细节和获得大量有机、生物有机和有机金属分子的分子组成的技术。它为化学家提供了表征化合物的最有力的工具之一。这种质谱仪在化学许多领域的前沿研究中是必不可少的。

This award from the Academic Research infrastructure Program will help the Department of Chemistry at Miami University acquire a Laser Desorption Time-of-Flight Mass Spectrometer which will be used in research. The research activity to be supported consists of two general parts: the development of methods to extend the capabilities of the laser desorption time-of- flight mass spectrometry and application of the technique to on-going research problems. Projects related to technique development include an investigation of the mechanism of matrix assistance and a study of the production of secondary ions. The proposed applications involve molecular biology, materials science, electrochemistry, and bioanalytical chemistry. Mass Spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic and organometallic molecules. It affords the chemist one of the most powerful tools available for the characterization of compounds. This mass spectrometer is essential for the prosecution of frontier research in many fields of chemistry.