Purchase of an Electrospray Ionization Ion Trap Mass Spectrometer

购买电喷雾电离离子阱质谱仪

• 批准号: 9613678
• 负责人: John Eyler
• 金额: $ 8.5万
• 依托单位: University of Florida
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-01 至 1998-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9613678&HistoricalAwards=false
• 关键词: Purchase; Electrospray; Ionization; Ion; Trap

This award from the Chemistry Research Instrumentation and Facilities Program will assist the Department of Chemistry at University of Florida acquire an electrospray ionization ion trap mass spectrometer. This equipment will enhance research in a number of areas including the following: (1) dynamic measurement of neuropeptides in vivo, (2) synthesis and characterization of synthetic and biological peptides and proteins, (3) electroactive polymers and aquathermolysis, (4) biocatalytic synthesis and biocatalytic conversion of aromatic wastes into useful compounds, and (5) analogs oligonucleotides and nucleosides bearing non-standard bases and modified bridging groups. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic,bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.

化学研究仪器和设施计划的这一奖项将帮助佛罗里达大学化学系获得电喷雾电离离子阱质谱仪。该设备将加强多个领域的研究，包括以下领域：（1）体内神经肽的动态测量，（2）合成和生物肽和蛋白质的合成和表征，（3）电活性聚合物和水凝胶，（4）芳香族废物的生物催化合成和生物催化转化为有用的化合物，和（5）带有非标准碱基和修饰的桥连基团的类似物寡核苷酸和核苷。 质谱（MS）是一种用于探测紧密结构细节并获得大量有机、生物有机和有机金属分子的分子组成的技术。 电喷雾技术的加入将质谱的范围扩展到蛋白质和核酸分子量，远远超过任何其他技术。电喷雾电离与高分辨率结合使用提供了质谱分析中可用的最新技术。 它为化学家提供了表征化合物的最强大的工具之一。在质谱分析中获得这种能力对于许多化学领域的前沿研究至关重要。