Studies of New Materials for Separations

该项目由纽约州立大学布法罗分校的助理教授Luis A.Colon指导，由化学系的分析和表面化学项目支持。这项工作将使用溶胶-凝胶技术来合成化学键合固定相，用于色谱学方法，特别是开柱和填充柱中的高效液相色谱(HPLC)和电色谱。在制备二氧化硅的过程中，将所需的官能团加入到溶胶凝胶试剂中，将产生不经历水解的硅-碳键，并提供多层材料。这些特性对于解决在高pH条件下适合分离的合适的填料和表面的存在问题特别有希望。将对影响玻璃形成过程中的化学反应的变量进行研究。许多技术(ESCA、SIMS、FTIR等)将被用来检查玻璃的物理化学性质，然后检查层析性能。总体目标是将工艺参数、材料特性和分离性能联系起来。液相色谱方法是将复杂的化合物混合物分离成其单独成分的强大技术。这项工作的目的是提供一种全新的方法来合成发生分离的材料。这种分离在环境分析、药物分析和许多其他领域得到了广泛的应用。该项目的重点是制造性能优于现有材料的材料。

This project, directed by Assistant Professor Luis A. Colon at SUNY-Buffalo, is supported by the Analytical and Surface Chemistry Program in the Division of Chemistry. The work will use sol-gel technology to synthesize chemically bonded stationary phases for use with chromatographic methods, particularly high performance liquid chromatography (HPLC) and electrochromatography in open and packed columns. The incorporation of the desired functional groups into the sol-gel reagents during the fabrication of the silica will create Si-C bonds that do not undergo hydrolysis and provide a material that is multilayered. These characteristics are especially promising for solving the existing problem of suitable packing and surfaces for separations at high pH. Studies will be done of the variables affecting the chemical reactions involved in the glass formation process. A number of techniques (ESCA, SIMS, FTIR and others) will be used to examine the physicochemical properties of the glasses, followed by examination of the chromatographic performance. The overall objective is to correlate the processing parameters, the material characteristics and the separation performance. Liquid chromatographic methods are powerful techniques to separate complex mixtures of compounds into their individual constituents. The purpose of this work is to provide an entirely new way to synthesize the materials upon which the separation takes place. Applications of such separations are wide-spread in areas such as environmental analysis, pharmaceutical analysis, and many others. The focus of the project is to make materials with properties superior to those now available.